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单词 plasmochin
释义

Plasmochinn.

Brit. /ˈplazməkɪn/, U.S. /ˈplæzmək(ə)n/
Forms: also with lower-case initial.
Origin: A borrowing from German. Etymon: German Plasmochin.
Etymology: < German Plasmochin (1926 or earlier: see P. Mühlens in Naturwissenschaften 14 (1926) 1162/1) < Plasmo- (in Plasmodium plasmodium n.) + -chin (in either Chinolin quinoline n. or Chinin quinine n.).The drug was developed by W. Schulemann, F. Schönhöfer, and A. Wingler in Germany c1925.
Pharmacology. Now chiefly historical.
= pamaquin n.
ΘΚΠ
the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations treating or preventing specific ailments > [noun] > for malaria
Plasmochin1926
Plasmoquine1926
atebrin1932
quinacrine1934
pamaquin1941
Paludrine1944
chloroquine1946
Resochin1946
proguanil1948
primaquine1949
hydroxychloroquine1951
pyrimethamine1952
mefloquine1974
qinghaosu1979
1926 Trade Marks Jrnl. 17 Mar. 631 Plasmochin... Chemical substances prepared for use in medicine and pharmacy.
1926 Lancet 16 Oct. 825/2 The great merits of plasmochin are that it is cheaper than quinine, tastes better, and gives rise to less unpleasant secondary effects.
1948 J. H. Burn Lect. Notes Pharmacol. 90 Pamaquin was introduced by the Germans as plasmochin; it is a quinoline derivative.
1962 J. H. Burn Drugs, Med. & Man xx. 197 Domagk was working in the Bayer fabrik in Elberfeld in Germany, where the advances had been made which led to the discovery of the antimalarial agents plasmochin and later atebrin.
1987 E. W. Burr Compan. Bird Med. xx. 122/1 Atebrin and Plasmochin reduced the number of gametocytes of H. columbae circulating in the blood of pigeons.
2004 Ambix 51 115 It was marketed under the name Plasmochin, and it was the first successful synthetic anti-malarial.
This entry has been updated (OED Third Edition, June 2006; most recently modified version published online March 2022).
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n.1926
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