单词 | phthiocol |
释义 | phthiocoln. Biochemistry. A yellow crystalline pigment, C11H8O3, originally isolated from tuberculosis bacilli, which has the action of vitamin K; 3-hydroxy-2-methyl-1,4-naphthoquinone. ΘΚΠ the world > life > biology > substance > pigment > [noun] > unspecified pigments > yellow safranine1868 lipochrome1887 carotenoid1913 phthiocol1933 cryptoxanthin1934 1933 R. J. Anderson & M. S. Newman in Jrnl. Biol. Chem. 103 197 In order to indicate its origin, we propose to designate the pigment by the name phthiocol. 1954 H. J. Almquist in W. H. Sebrell & R. S. Harris Vitamins II. ix. 393 Synthetic phthiocol tested with vitamin K-deficient chicks was found to be distinctly active in restoring normal blood-clotting time and thus became the first completely identified form of vitamin K. 1964 Asselineau & Lederer in V. C. Barry Chemotherapy of Tuberculosis i. 21 Phthiocol..isolated..after saponification of mycobacterial fat, is an artefact, produced from a vitamin K-like polyisoprenoid naphthoquinone. 1985 Jrnl. Org. Chem. 50 3358/1 Phthiocol, a metabolic product of the human tubercle bacillus, was analogously obtained in 86% yield from the quinone. This entry has been updated (OED Third Edition, March 2006; most recently modified version published online March 2022). < n.1933 |
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