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单词 phthiocol
释义

phthiocoln.

Brit. /ˈ(f)θʌɪəkɒl/, U.S. /ˈθaɪəˌkɔl/, /ˈθaɪəˌkɑl/
Origin: Perhaps a borrowing from Latin, combined with an English element. Perhaps formed within English, by compounding. Etymons: phthisis n., -o- connective, alcohol n., Latin color.
Etymology: < phthi- (in phthisis n.) + -o- connective + -col (perhaps representing alcohol n., with reference to its having been obtained by means of an alcohol-ether extract, or perhaps representing classical Latin color colour n.1, with reference to its being a pigment: see quot. 1933). Compare earlier phthioic adj.
Biochemistry.
A yellow crystalline pigment, C11H8O3, originally isolated from tuberculosis bacilli, which has the action of vitamin K; 3-hydroxy-2-methyl-1,4-naphthoquinone.
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the world > life > biology > substance > pigment > [noun] > unspecified pigments > yellow
safranine1868
lipochrome1887
carotenoid1913
phthiocol1933
cryptoxanthin1934
1933 R. J. Anderson & M. S. Newman in Jrnl. Biol. Chem. 103 197 In order to indicate its origin, we propose to designate the pigment by the name phthiocol.
1954 H. J. Almquist in W. H. Sebrell & R. S. Harris Vitamins II. ix. 393 Synthetic phthiocol tested with vitamin K-deficient chicks was found to be distinctly active in restoring normal blood-clotting time and thus became the first completely identified form of vitamin K.
1964 Asselineau & Lederer in V. C. Barry Chemotherapy of Tuberculosis i. 21 Phthiocol..isolated..after saponification of mycobacterial fat, is an artefact, produced from a vitamin K-like polyisoprenoid naphthoquinone.
1985 Jrnl. Org. Chem. 50 3358/1 Phthiocol, a metabolic product of the human tubercle bacillus, was analogously obtained in 86% yield from the quinone.
This entry has been updated (OED Third Edition, March 2006; most recently modified version published online March 2022).
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n.1933
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