phosphatidicadj.
/ˌfɒsfəˈtʌɪdɪk/, /ˌfɒsfəˈtɪdɪk/, U.S. /ˌfɑsfəˈtaɪdɪk/, /ˌfɑsfəˈtɪdɪk/ Biochemistry.
phosphatidic acid n. any of the esterified derivatives of glycerol phosphate in which the hydrogen atoms of both hydroxyl groups are replaced by fatty acid groups.
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the world > matter > chemistry > organic chemistry > organic acids > [noun] > carboxylic acids > functional derivatives
phthalic anhydride1855
monoglyceride1860
trimellitic acid1872
picolinic acid1876
thioglycollic acid1877
tetra-icosoic acid1894
phosphatidic acid1927
sialic acid1952
thioctic acid1952
1927 Channon & Chibnall in Biochem. Jrnl. 21 1115 It seems to us preferable to keep to Thudichum's original definitions [of phosphatide and cerebroside]. If this is done the diglyceridephosphoric acid and its salts are phosphatides. Since the acid is chemically the parent acid of the two more commonly occurring phosphatides lecithin and kephalin, we propose to call it phosphatidic acid.
1954 A. White et al. Princ. Biochem. v. 88 The phosphatides of known structure which contain one atom of N per atom of P may be regarded as derivatives of phosphatidic acid.
1979 Sci. Amer. Jan. 49/1 Two molecules of a fatty acid..are transferred from a donor to a molecule of glycerol phosphate, forming the most primitive phospholipid, phosphatidic acid.
1997 New Scientist 29 Nov. 25/2 Sent into overdrive by the drug, the enzyme floods the malignant cells with signalling substances called phosphatidic acids.
This entry has been updated (OED Third Edition, March 2006; most recently modified version published online March 2022).
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adj.1927