单词 | phorbol ester |
释义 | > as lemmasphorbol ester A crystalline tetracyclic alcohol, C20H28O6, present (in the form of strongly co-carcinogenic esters) in croton oil; (also) any of these esters. Frequently attributive, esp. in phorbol ester. ΘΚΠ the world > matter > chemistry > organic chemistry > substances from oils and fats > [noun] odorine1833 olein1838 palmitin1841 sericin1841 valerol1845 fuscin1864 safrole1869 anethene1872 methyl salicylate1876 salviol1877 isoeugenol1883 cineole1885 citronellal1890 coriandrol1891 tansy oil1894 arachin1905 ascaridol1908 phorbol1935 1935 Chem. Abstr. 29 2533 Phorbol (C20H28O6 or C20H30O6) with very dilute H2SO4 in N2 gives 38% crotophorbolon. 1939 Thorpe's Dict. Appl. Chem. (ed. 4) III. 434/2 Phorbol and the product of its benzoylation are physiologically inactive, but the (? tetra-)acetate is highly toxic. 1967 Naturwissenschaften 54 284/1 Phorbol esters show a true tumor promoting quality without accompanying tumorigenic activity provided the doses applied are small enough. 1994 Sci. Amer. June 64/2 The chemical [sc. prostratin]..was not being studied as a drug, because it was a phorbol, a class of chemicals that promotes the development of tumors. 2004 Tissue & Cell 36 149 Long-term exposure to the tumor promoter phorbol myristate acetate..affects Sertoli cell morphology, as well as actin and vinculin organization in vitro. < as lemmas |
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