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单词 phenylalanine
释义

phenylalaninen.

Brit. /ˌfiːnʌɪlˈaləniːn/, /ˌfiːn(ɪ)lˈaləniːn/, /ˌfiːnʌɪlˈalənʌɪn/, /ˌfiːn(ɪ)lˈalənʌɪn/, U.S. /ˌfɛnəlˈæləˌnin/, /ˌfinəlˈæləˌnin/
Origin: Formed within English, by compounding; modelled on a German lexical item. Etymons: phenyl n., alanine n.
Etymology: < phenyl n. + alanine n., after German Phenylalanin (E. Erlenmeyer & A. Lipp 1883, in Ann. der Chem. u. Pharm. 219 186).
Biochemistry.
A hydrophobic amino acid which occurs in many plant proteins and is an essential constituent of the human diet; 2-amino-3-phenylpropionic acid, C6H5CH2CH(NH2)COOH.
ΚΠ
1883 Jrnl. Chem. Soc. 44 992 Phenyl-α-amidoproprionic acid (phenylalanine),..obtained as a hydrochloride by pouring the crude product of the action of ammonia on phenylethylidine cyanhydrin into hydrochloric acid, and boiling the mixture.
1934 Times Lit. Suppl. 1 Nov. 758/3 Whether this represents a real ability to synthesize the amino-acid for all purposes, or simply a power to use dietary phenylalanine, remains an open question.
1955 Sci. News Let. 22 Jan. 52/1 Since phenylalanine poisoning caused the mental deficiency, Dr. Woolf decided to try devising a diet that would not contain this amino acid.
1967 Jrnl. Pediatrics 70 146/2 The assumption is generally made that phenylalanine or one of its metabolites is toxic to the developing brain.
1994 Health Naturally (Nobel, Ont.) Feb. 11/2 Phenylalanine should be avoided as a supplement, because high amounts can elevate blood pressure. This substance is found in large amounts in the ubiquitous artificial sweetener, aspartame.
This entry has been updated (OED Third Edition, December 2005; most recently modified version published online March 2022).
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n.1883
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