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单词 pethidine
释义

pethidinen.

Brit. /ˈpɛθᵻdiːn/, U.S. /ˈpɛθəˌdin/
Origin: Formed within English, by derivation. Etymons: piperidine n., ethyl n., -idine suffix.
Etymology: < p- (in piperidine n.) + eth- (in ethyl n.) + -idine suffix.
Pharmacology.
A synthetic opioid with properties similar to those of morphine, but with a shorter duration of action, used esp. for analgesia in childbirth. Cf. meperidine n.Chemical name: ethyl 1-methyl-4-phenylpiperidine-4-carboxylate, C15H21NO2. A proprietary name for this drug is Demerol n.
ΘΚΠ
the world > health and disease > healing > medicines or physic > medicines for specific purpose > analgesic > [noun] > other analgesics
Hoffmann's anodyne1747
acetylsalicylic acid1873
acetophenetidin1888
exalgin1889
pyramidon1898
aspirin1899
phenazone1899
Veganin1926
Trilene1935
Demerol1940
pethidine1942
Tridione1944
amidone1946
meperidine1947
methadone1947
Physeptone1947
Butazolidin1951
phenylbutazone1952
opioid1955
Panadol1955
propoxyphene1955
Tylenol1956
acetaminophen1957
paracetamol1957
Distalgesic1958
oxycodone1958
Sernyl1958
morphinomimetic1959
phencyclidine1959
levorphanol1960
mefenamic acid1962
pentazocine1964
Talwin1965
ibuprofen1967
nalbuphine1969
naproxen1971
phy1971
Nurofen1982
1942 Lancet 22 Aug. 234/2 Pethidine hydrochloride, a synthetic compound closely allied to morphine in composition, and combining the analgesic effect of morphine with the spasmolytic effect of the atropine group and papaverine, is issued by Roche Products.
1942 Lancet 24 Oct. 487 Fairly recent..is the carboxylic acid ethyl ester of 1-methyl-4-phenylpiperidine, officially named pethidine by the GMC a year ago and known on the continent as ‘Dolantin’ and in the United States as ‘Demerol’.
1955 Times 2 July 4/3 The annual Government report to the United Nations..estimates that there are 317 known drug addicts... Heroin and pethidine were used by 17 per cent. and 16 per cent. respectively.
1972 Nature 15 Dec. 411/2 Hysterotomy patients received pethidine 100 mg postoperatively for analgesia.
1995 Mother & Baby June 31/2 If you need something stronger, an injection of pethidine—a pain-relieving drug—can be given.
This entry has been updated (OED Third Edition, December 2005; most recently modified version published online March 2022).
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n.1942
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