phagedaenaphagedenan.

1567 T. Gale tr. Galen De Tumoribus preter Naturam xiii, in Certaine Wks. 374 Phagedena doth not only eate the skine, but the fleshe also, whiche is ioyned to it.

1575 J. Banister Needefull Treat. Chyrurg. f. 10^v Whose species or kinde is Phagedena, which is an ambulative Ulcer.

1583 P. Barrough Methode of Phisicke v. xvii. 239 Herpes doth not perfectly signifie among the Physitions malum quod serpit, but a certaine kinde of disease whereof we now entreate, therefore the creeping euil extendeth and stretcheth further then herpes for phagedænæ are also called serpentia vlcera, creeping vlcers.

1652 A. Ross Hist. World vi. 411 He was much troubled with a running Canker in the Foot, called by Physitians, Phagedena.

1676 R. Wiseman Severall Chirurg. Treat. ii. x. 193 Phagedæna,..is an Ulcer with swelled Lips, that eats the Flesh and neighbouring Parts in the bottome and edges of the Ulcer.

1703 W. Salmon Collectanea Medica ii. 332/2 That which is ulcerated is to be called Cancer, and Phagedena.

1705 J. Handley Colloquia Chirurgica xx. 65 But as for a Nome, or Ulcus depascens, it requires stronger Medicines than a Phagedœna.

1855 W. T. Helmuth Surg. & Adaptation into Homoeopathic Pract. 175 Mr. Miller mentions ten varieties [of ulcers]... The sloughing phagedæna.

1877 Jrnl. Statist. Soc. 40 226 In most large hospitals provision is now made for the separate treatment of patients suffering from traumatic erysipelas and phagedena in special wards.

1891 Lancet 3 Oct. 751 Formerly diseases peculiar to a hospital were the terror of the surgeon. Phagedæna attacked wounds even of the most trivial kind.

1982 Canad. Med. Assoc. Jrnl. 15 Feb. 363 Phagedena is an old term for serious deep, necrotic and gangrenous skin ulcers.

2003 Jrnl. Clin. Anesthesia 15 378 It [sc. necrotizing fasciitis] has been described as a putrid ulcer, phagedaena, and hospital gangrene.