penicillaminen.

Brit.

/ˌpɛnᵻˈsɪləmiːn/, U.S.

/ˌpɛnəˈsɪləˌmin/

Origin: Formed within English, by compounding. Etymons: penicillin n., amine n.

Etymology: < penicill- (in penicillin n.) + amine n.

Chemistry and Pharmacology.

A crystalline, sulphur-containing amino acid produced by the hydrolysis of penicillins, used pharmacologically as a chelating agent to remove heavy metals such as copper from the body, and as an anti-inflammatory agent, esp. for rheumatoid arthritis; 2-amino-3-methyl-3-mercaptobutanoic acid, (CH₃)₂C(SH)CH(NH₂)COOH.

ΘΚΠ

the world > health and disease > healing > medicines or physic > other miscellaneous medicines > [noun]

pesse1464

adarces1566

marmaritin1584

apostles' salt1605

methium?1608

panther1656

lenociny1657

aroph1658

fox-lungs1660

Dutch drops1843

penicillamine1943

1943 E. P. Abraham et al. in Nature 23 Jan. 107/1 The properties of this substance, which we propose to term penicillamine, show that it represents a novel type of naturally occurring base.

1967 Brain 90 154 Copper transport and excretion in normal individuals can be modified by the administration of the chelating agent penicillamine.

1977 Davidson's Princ. & Pract. Med. (ed. 12) 733 This disorder [sc. Wilson's disease]..can now be arrested by giving copper-binding drugs (chelating agents)... The most valuable of these is penicillamine.

2001 Guardian 10 Sept. i. 4/6 Other mistakes were giving penicillamine, for arthritis, rather than the antibiotic penicillin; and Lamictal, to control epilepsy, rather than Lamisil, an anti-fungal treatment.

This entry has been updated (OED Third Edition, September 2005; most recently modified version published online March 2022).

单词	penicillamine
释义	penicillaminen. Brit. /ˌpɛnᵻˈsɪləmiːn/, U.S. /ˌpɛnəˈsɪləˌmin/ Origin: Formed within English, by compounding. Etymons: penicillin n., amine n. Etymology: < penicill- (in penicillin n.) + amine n. Chemistry and Pharmacology. A crystalline, sulphur-containing amino acid produced by the hydrolysis of penicillins, used pharmacologically as a chelating agent to remove heavy metals such as copper from the body, and as an anti-inflammatory agent, esp. for rheumatoid arthritis; 2-amino-3-methyl-3-mercaptobutanoic acid, (CH₃)₂C(SH)CH(NH₂)COOH. ΘΚΠ the world > health and disease > healing > medicines or physic > other miscellaneous medicines > [noun] pesse1464 adarces1566 marmaritin1584 apostles' salt1605 methium?1608 panther1656 lenociny1657 aroph1658 fox-lungs1660 Dutch drops1843 penicillamine1943 1943 E. P. Abraham et al. in Nature 23 Jan. 107/1 The properties of this substance, which we propose to term penicillamine, show that it represents a novel type of naturally occurring base. 1967 Brain 90 154 Copper transport and excretion in normal individuals can be modified by the administration of the chelating agent penicillamine. 1977 Davidson's Princ. & Pract. Med. (ed. 12) 733 This disorder [sc. Wilson's disease]..can now be arrested by giving copper-binding drugs (chelating agents)... The most valuable of these is penicillamine. 2001 Guardian 10 Sept. i. 4/6 Other mistakes were giving penicillamine, for arthritis, rather than the antibiotic penicillin; and Lamictal, to control epilepsy, rather than Lamisil, an anti-fungal treatment. This entry has been updated (OED Third Edition, September 2005; most recently modified version published online March 2022). < n.1943
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