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单词 pepsinogen
释义

pepsinogenn.

Brit. /pɛpˈsɪnədʒ(ə)n/, U.S. /pɛpˈsɪnədʒ(ə)n/, /pɛpˈsɪnəˌdʒɛn/
Origin: Formed within English, by compounding; modelled on a German lexical item. Etymons: pepsin n., -ogen comb. form.
Etymology: < pepsin n. + -ogen comb. form, after German pepsinogen (adjective) in pepsinogene Substanz (W. Ebstein & P. Grützner 1874, in Archiv f. Physiol. 8 147). Compare German Pepsinogen (1897 or earlier).
Biochemistry.
Any of a series of proenzymes that are the precursors of the various forms of pepsin.
ΘΚΠ
the world > life > the body > secretory organs > secretion > gastric juice > [noun] > substance in
pepsin1844
pepsinogen1877
rennin1889
propeptone1890
thrombogen1890
intrinsic factor1930
1877 M. Foster Text Bk. Physiol. ii. i. 189 We have also evidence of the existence of a mother of pepsin or pepsinogen comparable to the pancreatic zymogen.
1974 V. B. Mountcastle et al. Med. Physiol. (ed. 13) II. 1186/1 Pepsinogen secretion continues at a high and sustained rate with continued stimulation.
2000 Oxf. Dict. Biochem. & Molecular Biol. (ed. 2) 490/1 Pepsinogens A, B, and C give rise to pepsin A, pepsin B, and pepsin C (i.e. gastricsin) respectively.
This entry has been updated (OED Third Edition, September 2005; most recently modified version published online March 2022).
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n.1877
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