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单词 phenethicillin
释义

phenethicillinn.

Brit. /fəˌnɛθᵻˈsɪlɪn/, /fɛˌnɛθᵻˈsɪlɪn/, U.S. /fəˌnɛθəˈsɪlᵻn/, /fɛˌnɛθəˈsɪlᵻn/
Forms: 1900s– phenethicillin, 1900s– pheneticillin.
Origin: Formed within English, by compounding. Etymons: pheno- comb. form, ethyl n., penicillin n.
Etymology: < pheno- comb. form + eth- (in ethyl n.) + -icillin (in penicillin n.).
Pharmacology.
A semi-synthetic penicillin.Chemical name: 6-(2-phenoxypropionamido)penicillanic acid, C17H20N2O5S.
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the world > health and disease > healing > medicines or physic > medicines for specific purpose > antibiotics > [noun] > penicillin > semi-synthetic
phenoxymethylpenicillin1947
Penbritin1959
phenethicillin1960
ampicillin1961
oxacillin1962
ticarcillin1972
1960 Brit. Med. Jrnl. 1 Oct. 994/2 When phenethicillin..was marketed as ‘broxil’, it was claimed that this preparation would give blood levels at least equal to those after intramuscular injection of corresponding doses of penicillin G.
1970 Daily Tel. 23 Oct. 13/3 The first semi-synthetic penicillin, phenethicillin, introduced in 1959, became widely used for the infections treated by family doctors.
1985 Brit. Jrnl. Clin. Pharmacol. 19 657 In this study the antimicrobial effects of phenoxymethylpenicillin (PM) and pheneticillin (PE) in vitro and in an experimental animal infection model were compared as well as the pharmacokinetic properties of both drugs in patients.
2003 FEMS Microbiol. Lett. 218 257 The enzymes showed excellent substrate conversion for penicillin G, phenethicillin, ampicillin and carbenicillin.
This entry has been updated (OED Third Edition, December 2005; most recently modified version published online March 2022).
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n.1960
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