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单词 pentolinium tartrate
释义

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pentolinium tartrate
A ganglion-blocking agent originally used in the treatment of severe hypertension; pentamethylene-1,5-bis-(1-methyl-pyrrolidinium) hydrogen tartrate, C23H42N2O12. More fully pentolinium tartrate.
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the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations treating or preventing specific ailments > [noun] > for blood-pressure disorders
Neo-Synephrine1934
Priscol1938
phenylephrine1947
hexamethonium1949
Priscoline1949
methonium1950
hydralazine1952
phentolamine1953
methyldopa1954
pentolinium1954
mecamylamine1955
hydrochlorothiazide1958
pempidine1958
guanethidine1959
hydroflumethiazide1959
thiazide1959
pheniprazine1960
pargyline1961
vasodepressor1961
alpha blocker1965
clonidine1969
prazosin1970
timolol1973
1954 Lancet 27 Nov. 1097/2 The preparation used was ‘Ansolysen’.., termed pentolinium tartrate by the British Pharmacopœia Commission in 1954.
1974 Prescribers Jrnl. 14 47 Ganglion blocking drugs, such as pentolinium..and pempidine.., have been omitted from this short review because..they have now been largely superseded.
1990 Philos. Trans. (Royal Soc.) B. 330 394 Pentolinium is selective for ganglionic nicotinic receptors, while the other three have mainly neuromuscular actions.
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