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单词 pentobarbital
释义

pentobarbitaln.

Brit. /ˌpɛntə(ʊ)ˈbɑːbᵻtl/, U.S. /ˌpɛn(t)əˈbɑrbədl/, /ˌpɛn(t)əˈbɑrbəˌtɔl/, /ˌpɛn(t)əˈbɑrbəˌtɑl/
Origin: Formed within English, by compounding. Etymons: pentane n., -o- connective, barbital n.
Etymology: < pent- (in pentane n.) + -o- connective + barbital n. Compare French penthiobarbital (20th cent.).
Pharmacology (originally U.S.).
A synthetic sedative-hypnotic and anticonvulsant barbituric drug which is usually used in the form of its sodium salt (more fully pentobarbital sodium, sodium pentobarbital); 5-ethyl-5-(1-methylbutyl)-barbituric acid, C11H18N2O3. Also called pentobarbitone.A proprietary name for the sodium salt is Nembutal. The British approved name was changed from pentobarbitone to pentobarbital in 1998.
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the world > health and disease > healing > medicines or physic > medicines for specific purpose > sedatives, antispasmodics, etc. > [noun]
Luminal1912
phenobarbital1919
Nembutal1930
pentobarbital1931
phenobarbitone1932
pentobarbitone1938
allobarbital1944
pheno1949
nembie1950
phenobarb1951
1931 Jrnl. Amer. Med. Assoc. 30 May 1871/1 Pentobarbital-sodium is a nonproprietary name given to the mono-sodium salt of ethyl-(1-methylbutyl) barbituric acid.
1955 Sci. News Let. 2 Apr. 219/2 The Boston doctors tested the effects of morphine, heroin, amphetamine, the sleeping medicine pentobarbital and as a control, sodium chloride.
1974 M. C. Gerald Pharmacol. xi. 204 Deep sedation is induced by the intravenous injection of amobarbital (Amytal) or pentobarbital (Nembutal).
1995 McGill Jrnl. Med. Spring 15/1 Nine adult Sprague-Dawley rats..were anesthetized with sodium pentobarbital.
This entry has been updated (OED Third Edition, September 2005; most recently modified version published online March 2022).
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n.1931
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