pentazocinen.

Brit.

/pɛnˈtazə(ʊ)siːn/, U.S.

/pɛnˈtæzəˌsin/,

/pɛnˈtæzəs(ə)n/

Origin: Formed within English, by derivation. Etymons: pentane n., azo- comb. form, octa- comb. form, -ine suffix⁵.

Etymology: < pent- (in pentane n.) + azo- comb. form + oc- (in octa- comb. form) + -ine suffix⁵ (with the ending -ocine thus denoting an 8-membered unsaturated heterocyclic molecule).

Pharmacology.

A synthetic opioid analgesic which is used for the control of moderate to severe pain, and which is less addictive than many other opioids but has a relatively short duration of action.A proprietary name for this drug is Talwin. Chemical name: 1,2,3,4,5,6-hexahydro-8-hydroxy-6,11-dimethyl-3-(3-methyl-2-butenyl)-2,6-methano-3-benzazocine.

ΘΚΠ

the world > health and disease > healing > medicines or physic > medicines for specific purpose > analgesic > [noun] > other analgesics

Hoffmann's anodyne1747

acetylsalicylic acid1873

acetophenetidin1888

exalgin1889

pyramidon1898

aspirin1899

phenazone1899

Veganin1926

Trilene1935

Demerol1940

pethidine1942

Tridione1944

amidone1946

meperidine1947

methadone1947

Physeptone1947

Butazolidin1951

phenylbutazone1952

opioid1955

Panadol1955

propoxyphene1955

Tylenol1956

acetaminophen1957

paracetamol1957

Distalgesic1958

oxycodone1958

Sernyl1958

morphinomimetic1959

phencyclidine1959

levorphanol1960

mefenamic acid1962

pentazocine1964

Talwin1965

ibuprofen1967

nalbuphine1969

naproxen1971

phy1971

Nurofen1982

1964 Jrnl. Pharmacol. & Exper. Therapeutics 143 142/1 (caption) Compound II has been assigned the generic name ‘pentazocine’ and Compound IV, ‘cyclazocine’.

1967 Observer 5 Mar. 13/1 Pentazocine, which in pain-killing potency falls between morphine and pethidine, becomes available in an injectable form (under the name Fortral) on 5 April.

1980 Lancet 16 Feb. 373/2 For our terminal patients with disseminated malignancy..we would not use pentazocine or meperidine: both drugs have a half-life of about two hours, necessitating two-hourly administration.

1999 Time 8 Mar. 71/3 (chart) In a study of dental patients, women responded more favorably than men to a class of pain relievers known as kappa opioids, including pentazocine.

This entry has been updated (OED Third Edition, September 2005; most recently modified version published online March 2022).

单词	pentazocine
释义	pentazocinen. Brit. /pɛnˈtazə(ʊ)siːn/, U.S. /pɛnˈtæzəˌsin/, /pɛnˈtæzəs(ə)n/ Origin: Formed within English, by derivation. Etymons: pentane n., azo- comb. form, octa- comb. form, -ine suffix⁵. Etymology: < pent- (in pentane n.) + azo- comb. form + oc- (in octa- comb. form) + -ine suffix⁵ (with the ending -ocine thus denoting an 8-membered unsaturated heterocyclic molecule). Pharmacology. A synthetic opioid analgesic which is used for the control of moderate to severe pain, and which is less addictive than many other opioids but has a relatively short duration of action.A proprietary name for this drug is Talwin. Chemical name: 1,2,3,4,5,6-hexahydro-8-hydroxy-6,11-dimethyl-3-(3-methyl-2-butenyl)-2,6-methano-3-benzazocine. ΘΚΠ the world > health and disease > healing > medicines or physic > medicines for specific purpose > analgesic > [noun] > other analgesics Hoffmann's anodyne1747 acetylsalicylic acid1873 acetophenetidin1888 exalgin1889 pyramidon1898 aspirin1899 phenazone1899 Veganin1926 Trilene1935 Demerol1940 pethidine1942 Tridione1944 amidone1946 meperidine1947 methadone1947 Physeptone1947 Butazolidin1951 phenylbutazone1952 opioid1955 Panadol1955 propoxyphene1955 Tylenol1956 acetaminophen1957 paracetamol1957 Distalgesic1958 oxycodone1958 Sernyl1958 morphinomimetic1959 phencyclidine1959 levorphanol1960 mefenamic acid1962 pentazocine1964 Talwin1965 ibuprofen1967 nalbuphine1969 naproxen1971 phy1971 Nurofen1982 1964 Jrnl. Pharmacol. & Exper. Therapeutics 143 142/1 (caption) Compound II has been assigned the generic name ‘pentazocine’ and Compound IV, ‘cyclazocine’. 1967 Observer 5 Mar. 13/1 Pentazocine, which in pain-killing potency falls between morphine and pethidine, becomes available in an injectable form (under the name Fortral) on 5 April. 1980 Lancet 16 Feb. 373/2 For our terminal patients with disseminated malignancy..we would not use pentazocine or meperidine: both drugs have a half-life of about two hours, necessitating two-hourly administration. 1999 Time 8 Mar. 71/3 (chart) In a study of dental patients, women responded more favorably than men to a class of pain relievers known as kappa opioids, including pentazocine. This entry has been updated (OED Third Edition, September 2005; most recently modified version published online March 2022). < n.1964
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