单词 | parasympathomimetic |
释义 | parasympathomimeticadj.n. Pharmacology and Physiology. A. adj. Producing physiological effects similar to those produced by stimulation of the parasympathetic nervous system; (also) of the nature of such effects. ΘΚΠ the world > health and disease > healing > medicines or physic > drugs having specific effect > [adjective] > parasympathomimetic parasympatheticomimetic1933 parasympathomimetic1933 1933 Proc. Royal Soc. B. 112 248 Poos (1927) was unable to find any effect of the parasympatho-mimetic drugs on the isolated dilatator of mammals. 1940 Q. Jrnl. Med. 9 239 Observations on the effect of parasympathetic-mimetic drugs have been made.] 1946 Jrnl. Pharmacol. & Exper. Therapeutics 87 31 A range of doses of eleven parasympathomimetic drugs (acetylcholine, mecholyl, [etc.]..) was administered subcutaneously. 1968 W. C. Bowman et al. Textbk. Pharmacol. xxviii. 702 In addition to their important muscarinic actions, many parasympathomimetic drugs exert other actions at different sites. For example, acetylcholine itself..stimulates ganglion cells and striated muscle. 1974 Ann. Internal Med. 81 49/1 All parasympathomimetic maneuvers and drugs affect arrhythmias by causing local release of acetylcholine in cardiac tissues. 1974 M. C. Gerald Pharmacol. v. 103 Analogous terms are used for drugs modifying cholinergic activity, that is, cholinergic or parasympathomimetic agents and cholinergic blocking agents. 1987 M. J. Neal Med. Pharmacol. at Glance vii. 21/2 Muscarinic effects are mainly parasympathomimetic (except sweating and vasodilation). 1993 S. J. Ettinger Pocket Compan. Textbk. Vet. Internal Med. lxxiii. 333 Parasympathomimetic drugs may exacerbate the vagal effects of digitalis. B. n. A parasympathomimetic agent. ΘΚΠ the world > health and disease > healing > medicines or physic > drugs having specific effect > [noun] > parasympathomimetic parasympatheticomimetic1931 parasympathomimetic1960 1960 Science 7 Oct. 955/1 Parasympathomimetics..have a high intrinsic activity, whereas..parasympatholytics..have a very low intrinsic activity. 1972 Exper. Neurol. 34 355 (heading) The central activity of parasympathomimetics on gastric secretory function. 1994 Brit. National Formulary Mar. i. 44/2 The parasympathomimetics bethanechol, distigmine, reostigmine, and pyridostigmine..enhance parasympathetic activity in the gut and increase intestinal motility. This entry has been updated (OED Third Edition, June 2005; most recently modified version published online March 2022). < adj.n.1933 |
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