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单词 paraneoplastic
释义

paraneoplasticn.

Brit. /ˌparəniːə(ʊ)ˈplastɪk/, U.S. /ˈˌpɛrəˌnioʊˈplæstɪk/
Origin: Formed within English, by derivation; modelled on a French lexical item. Etymons: para- prefix1, neoplastic adj.1
Etymology: < para- prefix1 + neoplastic adj.1, after French paranéoplastique (1957 in the source translated in quot. 1957).
Medicine.
Designating or relating to any of various (often metabolic, endocrine, or neurological) conditions which occur in patients with neoplastic disease but which do not result directly from tissue invasion by the primary tumour or its metastases; esp. in paraneoplastic syndrome.
ΚΠ
1957 Current List Med. Lit. 32 R-155/1 3 new cases of paraneoplastic polyneuritis of refractory type.
1977 Ann. Internal Med. 86 664/2 The other patient had primary carcinoma of the liver; the hypercalcemia evidently was due to paraneoplastic hyperparathyroidism, because no metastases were found at autopsy.
1993 S. J. Ettinger Pocket Compan. Textbk. Vet. Internal Med. lxix. 315 Hypertrophic pulmonary osteopathy is the most frequently reported paraneoplastic syndrome in dogs.
2000 Brit. Med. Jrnl. 8 July The ‘internal’ environment accounts for paraneoplastic autoimmune associations of cancers of the ovary, lung, and breast in which an antigen associated with the tumour provokes remarkable autoimmune responses that damage structures such as cerebellar, motor, or sensory neurones.
This is a new entry (OED Third Edition, June 2005; most recently modified version published online March 2022).
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n.1957
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