parakeratosisn.
/ˌparəkɛrəˈtəʊsɪs/, U.S. /ˈˌpɛrəˌkɛrəˈtoʊsəs/ Pathology and Medicine.
Originally: abnormal keratinization or cornification; any disorder characterized by this. Later: spec. retention of nuclei by cells of the stratum corneum, as a normal or abnormal finding.
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the world > health and disease > ill health > a disease > disorders of visible parts > skin disorders > [noun] > hardening or thickening
callosity?a1425
callousness1634
imperspirability1745
hyperkeratosis1841
scleroderma1873
sclerodermia1873
parakeratosis1885
acanthosis1887
tylosis1890
lichenification1892
sclerœdema1932
1885 tr. H. Auspitz in tr. H. W. von Ziemssen et al. Handbk. Dis. Skin 103 According as an exaggeration, a diminution, or a deviation from the type of development predominates, they may be termed hyperkeratosis, keratolysis, or parakeratosis.
1896 N. Walker tr. P. G. Unna Histopathol. Dis. Skin 69 The ultimate sub-division of this class of dermatoses is into moist and dry cutaneous catarrh: into ‘Eczematosis’ and ‘Parakeratosis’.
1899 T. C. Allbutt et al. Syst. Med. VIII. 882 Bowen..regards the disease as a parakeratosis.
1948 R. H. Follis Pathol. Nutritional Dis. 219 The lining of the base of the tongue exhibits parakeratosis in zinc-deficient rats.
1960 Farmer & Stockbreeder 16 Feb. (Suppl.) 34 Concentrated Mindif Mineral Salts. Contains calcium and phosphorus with trace elements including zinc for the prevention of Parakeratosis (dry feeding mange).
1970 Arch. Dermatol. 101 346/2 Parakeratosis is generally recognized as histologic evidence of an increased turnover of epidermal cells.
1988 BioFactors 1 35/2 Hyperkeratosis and parakeratosis of the skin are prominent abnormalities.
2000 Jrnl. European Acad. Dermatol. & Venereol. 14 97 There was no evidence of parakeratosis or any other histological characteristic of psoriasis.
This entry has been updated (OED Third Edition, June 2005; most recently modified version published online March 2022).
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n.1885