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单词 papaverine
释义

papaverinen.

Brit. /pəˈpeɪvəriːn/, /pəˈpavəriːn/, /pəˈpeɪvərɪn/, /pəˈpavərɪn/, U.S. /pəˈpævəˌrin/, /pəˈpævərən/
Origin: A borrowing from Latin, combined with an English element; modelled on a German lexical item. Etymons: Latin papāver , -ine suffix5.
Etymology: < classical Latin papāver poppy (see papaverous adj.) + -ine suffix5, after German Papaverin (G. Merck 1848, in Ann. der Chem. u. Pharm. 66 126). Compare French papavérine (1842).
Chemistry.
A crystalline alkaloid, C20H21NO4, which is a minor constituent of opium and is used, chiefly in the form of a hydrochloride, as a smooth muscle relaxant and vasodilator.
ΘΚΠ
the world > matter > chemistry > organic chemistry > alkaloids > [noun] > miscellaneous other
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1848 tr. G. Merck in Chem. Gaz. 6 309 I have now succeeded in discovering a new base in the residues from the preparation of morphine, which I shall call papaverine.
1876 J. Harley Royle's Man. Materia Med. (ed. 6) 762 Opium contains about 1 per cent. of Papaverine.
1946 Brit. Jrnl. Pharmacol. 1 99 Pethidine, phenacaine and papaverine possess both aromatic and basic groups and have a quinidine-like action.
1989 Chem. Senses 14 819 For experiments using adenosine 5′ monophosphate as the odorant, papaverine hydrochloride was the phosphodiesterase inhibitor.
1991 J. Hersey Antonietta 26 She could not get a good night's sleep without taking a powder of opium, dried garlic, henbane, and papaverine.
This entry has been updated (OED Third Edition, March 2005; most recently modified version published online March 2022).
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n.1848
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