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单词 oxazolone
释义

oxazolonen.

Brit. /ɒkˈseɪzələʊn/, /ɒkˈsazələʊn/, U.S. /ɑkˈsæzəloʊn/
Origin: Formed within English, by derivation. Etymons: oxazole n., -one suffix.
Etymology: < oxazole n. + -one suffix.
Chemistry.
Any of a class of compounds resembling oxazoles but with the CH:CH part of the oxazole ring replaced by CO·CH2; spec. the parent compound C3H3NO2.
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the world > matter > chemistry > organic chemistry > organic compounds > [noun] > other organic compounds
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CFC1976
1899 F. R. Japp & A. Findlay in Jrnl. Chem. Soc. 75 i. 1027 It occurred to us that, by substituting an α-hydroxy-acid for the α-keto-alcohol in the foregoing reaction, it might be possible to prepare oxazolones (ketodihydro-oxazoles).
1947 Sci. News 4 70 The synthesis of penicillin G starts with a benzyl oxazolone and with penicillamine, and attempts to recombine them.
1968 R. O. C. Norman Princ. Org. Synthesis xviii. 604 The oxazolones or azlactones, prepared by the dehydration of N-acyl-α-amino-acids, are employed in Erlenmeyer's synthesis of α-amino-acids.
1998 New Scientist 29 Aug. 4/3 This led to a 69 per cent reduction in the animal's immune response to the chemical oxazolone, which causes inflammation.
This entry has been updated (OED Third Edition, March 2005; most recently modified version published online March 2022).
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n.1899
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