oxazolidinen.
/ˌɒksəˈzəʊlᵻdiːn/, U.S. /ˌɑksəˈzoʊləˌdin/ Chemistry.
Any substituted derivative of the hypothetical heterocyclic compound C3H7NO (which is the fully hydrogenated form of oxazole), some of which act as anticonvulsants.
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oxazolidine1902
1902 Jrnl. Chem. Soc. 82 i. 56 (heading) Synthesis of oxazolidines by the action of aldehydes on hydramines.
1953 Chem. Rev. 53 315 The oxazolidines are liquids or solids of basic character; their stability to hydrolysis is generally low.
1961 A. Goth Med. Pharmacol. xix. 229 In the clinical use of the oxazolidine derivatives, the following toxic effects have been reported: drowsiness and ataxia, photophobia, and a strange visual disturbance.
2001 Guardian 4 Oct. (Online section) 11/6 They have found that a focused beam of microwaves can trigger the reaction of a group of readily available amino-alcohols with an aldehyde to form a so-called oxazolidine.
This entry has been updated (OED Third Edition, March 2005; most recently modified version published online March 2022).
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