oxamniquinen.

Brit.

/ˌɒkˈsamnɪkwɪn/, U.S.

/ɑkˈsæmnəˌkwin/,

/ɑkˈsæmnəkwən/

Origin: Formed within English, by compounding. Etymons: oxy- comb. form², amino- comb. form, quinoline n.

Etymology: < oxy- comb. form² + -amni- (perhaps < a rearrangement of letters in amino- comb. form) + -quine ( < quin- in quinoline n., remodelled after -ine suffix⁵).

Pharmacology.

An anthelmintic drug given orally for the treatment of intestinal schistosomiasis ( Schistosoma mansoni infestation); 1,2,3,4-tetrahydro-2-isopropylaminomethyl-7-nitro-6-quinolyl-methanol, C₁₄H₂₁N₃O₃.

ΘΚΠ

the world > health and disease > healing > medicines or physic > medicines for specific purpose > remedies for parasitic infections > [noun] > vermifuge or anthelminthic > others

brayera1875

piperazine1889

piperazidine1891

hexylresorcinol1924

thiabendazole1961

niridazole1966

tetramisole1966

mebendazole1971

oxamniquine1972

albendazole1976

1972 Approved Names (Brit. Pharmacopœia Comm.) Suppl. iv. 5 Oxamniquine.

1973 Trans. Royal Soc. Trop. Med. & Hygiene 67 679 Puerto Rican worms derived from the survivors of treatment of a previous generation with a sub-curative dose of oxamniquine were as susceptible to the drug as were their parents.

1985 Ann. Rev. Pharmacol. & Toxicol. 25 489 In every case where hycanthone-resistant S. mansoni worms have been isolated from either man or animals, they have been found to be resistant to oxamniquine also.

1995 Pharmacol. & Therapeutics 68 35 The reported occurrence of drug-resistant schistosomes after treatment with oxamniquine and praziquantel suggests strict monitoring of such phenomena.

This entry has been updated (OED Third Edition, March 2005; most recently modified version published online March 2022).

单词	oxamniquine
释义	oxamniquinen. Brit. /ˌɒkˈsamnɪkwɪn/, U.S. /ɑkˈsæmnəˌkwin/, /ɑkˈsæmnəkwən/ Origin: Formed within English, by compounding. Etymons: oxy- comb. form², amino- comb. form, quinoline n. Etymology: < oxy- comb. form² + -amni- (perhaps < a rearrangement of letters in amino- comb. form) + -quine ( < quin- in quinoline n., remodelled after -ine suffix⁵). Pharmacology. An anthelmintic drug given orally for the treatment of intestinal schistosomiasis ( Schistosoma mansoni infestation); 1,2,3,4-tetrahydro-2-isopropylaminomethyl-7-nitro-6-quinolyl-methanol, C₁₄H₂₁N₃O₃. ΘΚΠ the world > health and disease > healing > medicines or physic > medicines for specific purpose > remedies for parasitic infections > [noun] > vermifuge or anthelminthic > others brayera1875 piperazine1889 piperazidine1891 hexylresorcinol1924 thiabendazole1961 niridazole1966 tetramisole1966 mebendazole1971 oxamniquine1972 albendazole1976 1972 Approved Names (Brit. Pharmacopœia Comm.) Suppl. iv. 5 Oxamniquine. 1973 Trans. Royal Soc. Trop. Med. & Hygiene 67 679 Puerto Rican worms derived from the survivors of treatment of a previous generation with a sub-curative dose of oxamniquine were as susceptible to the drug as were their parents. 1985 Ann. Rev. Pharmacol. & Toxicol. 25 489 In every case where hycanthone-resistant S. mansoni worms have been isolated from either man or animals, they have been found to be resistant to oxamniquine also. 1995 Pharmacol. & Therapeutics 68 35 The reported occurrence of drug-resistant schistosomes after treatment with oxamniquine and praziquantel suggests strict monitoring of such phenomena. This entry has been updated (OED Third Edition, March 2005; most recently modified version published online March 2022). < n.1972
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