oxacillinn.
/ˌɒksəˈsɪlɪn/, U.S. /ˌɑksəˈsɪlᵻn/ Pharmacology.
A semi-synthetic penicillin that is resistant to penicillinase; (5-methyl-3-phenyl-4-isoxazolyl)-penicillin sodium, C19H18N3O5NaS.H2O. More fully oxacillin sodium, sodium oxacillin.
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the world > health and disease > healing > medicines or physic > medicines for specific purpose > antibiotics > [noun] > penicillin > semi-synthetic
phenoxymethylpenicillin1947
Penbritin1959
phenethicillin1960
ampicillin1961
oxacillin1962
ticarcillin1972
1962 Proc. Mayo Clinic 37 137 5-Methyl-3-phenyl-4-isoxazolyl penicillin... Since this paper was prepared for publication, ‘oxacillin’ has been adopted as the generic name of this drug.
1967 Martindale's Extra Pharmacopoeia (ed. 25) 994/1 Oxacillin sodium is more resistant to destruction by the acid gastric secretion than benzylpenicillin or methicillin sodium.
1970 Atlantic Monthly Mar. 50 He was also given heavy doses of antibiotics, including a gram of chloramphenicol, a gram of oxacillin, [etc.].
1993 S. J. Ettinger Pocket Compan. Textbk. Vet. Internal Med. lxii. 258 Antibiotics that are most effective are cephalosporins, or penicillinase-resistant penicillins such as oxacillin and cloxacillin.
This entry has been updated (OED Third Edition, March 2005; most recently modified version published online March 2022).
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n.1962