单词 | osteolathyrism |
释义 | > as lemmasosteolathyrism osteolathyrism n. Brit. /ˌɒstɪə(ʊ)ˈlaθᵻrɪz(ə)m/ , U.S. /ˌɑstioʊˈlæθəˌrɪz(ə)m/ abnormalities of connective tissue, esp. in bones and blood vessels, resulting from the consumption of seeds of certain plants of the genus Lathyrus or certain nitriles.ΘΚΠ the world > health and disease > ill health > animal disease or disorder > disorders of animals generally > [noun] > other disorders bunnyc1440 cold1486 big-head1805 dwarfism1833 milk fever1860 fagopyrism1895 hyperdactyly1902 myelocytoma1929 osteofibrosis1936 mousepox1947 osteolathyrism1957 whitepox1996 1957 H. Selye in Revue Canad. de Biol. 16 1 An apparently quite unrelated skeletal disease, ‘osteolathyrism’, can be induced experimentally in laboratory animals by feeding them the seeds of other types of Lathyrus plants, especially L. odoratus. The active principle of the latter is aminopropionitrile. 1971 Sci. Amer. June 51/1 One form of this disease, called osteolathyrism, can be produced experimentally in animals by administering aminonitriles and related compounds. In osteolathyrism the inhibition of cross-links in elastin and collagen brings about structural abnormalities in the connective tissues, particularly those of blood vessels and bone. 1997 Natural Toxins 5 43 In a study of 500 patients suffering from neurolathyrism in Bangladesh it was found that 60 (all male) complained of bone pain and showed skeletal deformities suggestive of osteolathyrism. < as lemmas |
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