osteoclastoman.

Brit.

/ˌɒstɪəʊklɑːˈstəʊmə/,

/ˌɒstɪəʊklaˈstəʊmə/, U.S.

/ˈˌɑstioʊˌklæˈstoʊmə/

Inflections: Plural osteoclastomas, osteoclastomata.

Origin: Formed within English, by compounding. Etymons: osteoclast n., -oma comb. form.

Etymology: < osteoclast n. + -oma comb. form.

Pathology.

An osteolytic tumour of bone, usually benign, composed of giant cells of osteoclastic type and stromal cells; also called giant cell tumour of bone. Also: a localized area of increased osteoclastic activity, seen in certain disorders or tumours of bone (now rare).

ΘΚΠ

the world > health and disease > ill health > a disease > diseases of tissue > disorders of bones > [noun] > tumour

osteosarcoma1804

chloroma1886

Ewing1924

osteoclastoma1926

1926 Jrnl. Pathol. & Bacteriol. 29 399 (heading) A case of osteoclastoma (myeloid sarcoma, benign giant-cell tumour) with pulmonary metastasis.

1931 Brit. Jrnl. Surg. 19 242 Generalized osteitis fibrosa with multiple osteoclastomata.

1948 R. A. Willis Pathol. Tumours xliii. 680 The changing views regarding the nature of this tumour have resulted in a diverse and confusing terminology—‘myeloma’, ‘myeloid sarcoma’, ‘tumeur à myéloplaxes’, ‘benign giant-cell tumour’, ‘osteoclastoma’, and ‘chronic (non-suppurative) hemorrhagic osteomyelitis’, being only some of the names applied to it.

1961 Lancet 30 Sept. 751/2 Osteoclastomas respond well to irradiation.

1974 R. Passmore & J. S. Robson Compan. Med. Stud. III. i. xxvi. 31/1 Giant cell tumour (osteoclastoma)... The nature of the cells is not definitely known, but the possibility that the giant cells are osteoclasts has led to the alternative name, osteoclastoma.

1981 R. N. Hardy Endocrine Physiol. ii. 15 Many patients have no obvious bone disease, while others may show signs of generalized decalcification and sometimes the formation of bone cysts (osteitis fibrosa cystica) or giant cell pseudotumours consisting mainly of osteoclasts (osteoclastomas).

2000 Jrnl. Orthopedic Res. 18 800 The expression was further compared with that detected in the inflamed synovial membranes from patients with rheumatoid arthritis or osteoarthritis..and one patient with osteoclastoma (giant cell tumour of bone).

This entry has been updated (OED Third Edition, September 2004; most recently modified version published online March 2022).

单词	osteoclastoma
释义	osteoclastoman. Brit. /ˌɒstɪəʊklɑːˈstəʊmə/, /ˌɒstɪəʊklaˈstəʊmə/, U.S. /ˈˌɑstioʊˌklæˈstoʊmə/ Inflections: Plural osteoclastomas, osteoclastomata. Origin: Formed within English, by compounding. Etymons: osteoclast n., -oma comb. form. Etymology: < osteoclast n. + -oma comb. form. Pathology. An osteolytic tumour of bone, usually benign, composed of giant cells of osteoclastic type and stromal cells; also called giant cell tumour of bone. Also: a localized area of increased osteoclastic activity, seen in certain disorders or tumours of bone (now rare). ΘΚΠ the world > health and disease > ill health > a disease > diseases of tissue > disorders of bones > [noun] > tumour osteosarcoma1804 chloroma1886 Ewing1924 osteoclastoma1926 1926 Jrnl. Pathol. & Bacteriol. 29 399 (heading) A case of osteoclastoma (myeloid sarcoma, benign giant-cell tumour) with pulmonary metastasis. 1931 Brit. Jrnl. Surg. 19 242 Generalized osteitis fibrosa with multiple osteoclastomata. 1948 R. A. Willis Pathol. Tumours xliii. 680 The changing views regarding the nature of this tumour have resulted in a diverse and confusing terminology—‘myeloma’, ‘myeloid sarcoma’, ‘tumeur à myéloplaxes’, ‘benign giant-cell tumour’, ‘osteoclastoma’, and ‘chronic (non-suppurative) hemorrhagic osteomyelitis’, being only some of the names applied to it. 1961 Lancet 30 Sept. 751/2 Osteoclastomas respond well to irradiation. 1974 R. Passmore & J. S. Robson Compan. Med. Stud. III. i. xxvi. 31/1 Giant cell tumour (osteoclastoma)... The nature of the cells is not definitely known, but the possibility that the giant cells are osteoclasts has led to the alternative name, osteoclastoma. 1981 R. N. Hardy Endocrine Physiol. ii. 15 Many patients have no obvious bone disease, while others may show signs of generalized decalcification and sometimes the formation of bone cysts (osteitis fibrosa cystica) or giant cell pseudotumours consisting mainly of osteoclasts (osteoclastomas). 2000 Jrnl. Orthopedic Res. 18 800 The expression was further compared with that detected in the inflamed synovial membranes from patients with rheumatoid arthritis or osteoarthritis..and one patient with osteoclastoma (giant cell tumour of bone). This entry has been updated (OED Third Edition, September 2004; most recently modified version published online March 2022). < n.1926
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