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单词 orosomucoid
释义

orosomucoidn.

Brit. /ˌɔːrə(ʊ)sə(ʊ)ˈmjuːkɔɪd/, U.S. /ˈˌɔroʊsoʊˈmjuˌkɔɪd/
Origin: A borrowing from Greek, combined with English elements. Etymons: Greek ὀρός , -o- connective, mucoid n.
Etymology: < ancient Greek ὀρός serum (see orotic adj.) + -o- connective + mucoid n.
Biochemistry and Medicine.
A plasma glycoprotein that is involved in the maintenance of normal capillary permeability, and that occurs at elevated concentrations in inflammation.Also called α1-acid glycoprotein.
ΘΚΠ
the world > life > biology > substance > proteins > [noun]
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orosomucoid1955
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1955 R. J. Winzler in Methods Biochem. Anal. 2 281 The major component in human seromucoid is an electrophoretically and ultracentrifugally distinct acidic glycoprotein which has been crystallized and quite well characterized by chemical, physical, and immunological methods... It is appropriate to assign to this protein the name orosomucoid..to indicate its source and nature.
1965 Biochimica et Biophysica Acta 101 336 The human and bovine orosomucoids had molecular weights of 41 600 and 37 300 respectively by the sedimentation diffusion method.
1972 Res. Communications Chem. Pathol. & Pharmacol. 3 663 Important increases in the level of orosomucoid accompany exudative inflammatory processes.
1982 T. M. Devlin Textbk. Biochem. iii. 122 In the plasma protein human orosomucoid there are nine asparagine residues.
2002 Diabetologia 45 115 We found that urinary orosomucoid excretion rate predicted all-cause and cardiovascular mortality in patients with Type II diabetes.
This entry has been updated (OED Third Edition, September 2004; most recently modified version published online March 2022).
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n.1955
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