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单词 ondansetron
释义

ondansetronn.

Brit. /ɒnˈdansətrɒn/, U.S. /ɑnˈdænsəˌtrɑn/
Origin: Of unknown origin.
Etymology: Origin unknown.
Pharmacology.
A carbazole derivative, C18H19N3O, that is a serotonin receptor antagonist administered by injection and by mouth to relieve nausea and vomiting, esp. during cancer therapy.
ΚΠ
1988 Brit. Approved Names 1986 (Brit. Pharmacopoeia Comm.) Suppl. v. 5 Ondansetron.
1990 New Scientist 25 Aug. 25/3 Specifically, ondansetron blocks the class of receptors known as 5-HT3 receptors.
1995 C. Sagan Demon-haunted World xiii. 230 Consider the nausea and vomiting that frequently accompany the chemotherapy given to cancer and AIDS patients... The drug ondansetron hydrochloride greatly reduces the incidence of these symptoms; but is it actually the drug or the expectation of relief?
2002 Plastic & Reconstructive Surg. 109 2487 Ondansetron (Zofran) has proven benefit in preventing postoperative nausea and vomiting if given before general anesthesia.
This is a new entry (OED Third Edition, June 2004; most recently modified version published online March 2022).
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n.1988
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