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单词 oncoprotein
释义

oncoproteinn.

Brit. /ˌɒŋkə(ʊ)ˈprəʊtiːn/, U.S. /ˌɑnkoʊˈproʊˌtin/, /ˌɑŋkoʊˈproʊˌtin/
Origin: Formed within English, by compounding. Etymons: onco- comb. form, protein n.
Etymology: < onco- comb. form + protein n.
Genetics.
A protein encoded by an oncogene and able to cause the transformation of a cell into a tumour cell if introduced into it.
ΚΠ
1983 Proc. National Acad. Sci. U.S.A. 80 5276/1 The amino acid sequence..is reminiscent of..other viral oncoproteins.
1991 Oncogene 6 543 Our results suggest that the oncoprotein plays a crucial role in T-cell transformation by HTLV-1.
1997 Jrnl. Gen. Virol. 78 3001 The E6 oncoprotein of human papillomavirus..binds and degrades the tumour suppressor protein p53, thus contributing to tumour progression.
2002 Oncol. Rep. 9 557 Human breast cancers..often overexpress the oncoprotein MDM2 without mdm2 gene amplification.
This is a new entry (OED Third Edition, June 2004; most recently modified version published online March 2022).
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n.1983
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