单词 | oncogene |
释义 | oncogenen. Virology. A gene whose products may in certain circumstances transform a cell containing them into a tumour cell. ΘΚΠ the world > life > biology > biological processes > genetic activity > genetic components > [noun] > gene > types of gene sex determinant1902 sex determiner1909 inhibitor1911 multiple factor1912 modifier1915 autosomal dominant1919 autosomal recessive1919 scute1923 gene1925 suppressor1928 rate gene1932 dominigene1938 buffer1939 polygene1941 switch gene1942 mutator1943 oligogene1943 sickle cell gene1946 supergene1949 ob1950 obese1950 regulator1960 regulator gene1960 regulatory gene1960 enhancer1967 oncogene1969 virogene1969 hedgehog1980 1969 R. J. Huebner & G. J. Todaro in Proc. National Acad. Sci. U.S.A. 64 1087 It is postulated that the viral information (the virogene), including that portion responsible for transforming a normal cell into a tumor cell (the oncogene), is most commonly transmitted from animal to progeny animal and from cell to progeny cell in a covert form. 1984 J. R. Tighe & D. R. Davies Pathol. (ed. 4) x. 85 As a result of this substitution, the oncogene directs the synthesis of an abnormal protein. 1994 B. Alberts et al. Molecular Biol. Cell (ed. 3) 768 The mutant genes were called oncogenes before their origin from normal genes was understood; the normal genes are therefore sometimes referred to as proto-oncogenes. 2000 Z. Smith White Teeth (2001) xii. 340 Now you're talking the genetic program of the mouse, a force activating oncogenes within cells. This entry has been updated (OED Third Edition, June 2004; most recently modified version published online March 2022). < n.1969 |
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