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单词 opioid
释义

opioidn.adj.

Brit. /ˈəʊpɪɔɪd/, U.S. /ˈoʊpiˌɔɪd/
Origin: Formed within English, by derivation. Etymons: opium n., -oid suffix.
Etymology: < opium n. + -oid suffix.
Pharmacology and Biochemistry.
A. n.
Originally: any synthetic narcotic drug derived from or having properties similar to those of morphine. Later also: an opiate (opiate n. 1a).
ΘΚΠ
the world > health and disease > healing > medicines or physic > medicines for specific purpose > analgesic > [noun] > other analgesics
Hoffmann's anodyne1747
acetylsalicylic acid1873
acetophenetidin1888
exalgin1889
pyramidon1898
aspirin1899
phenazone1899
Veganin1926
Trilene1935
Demerol1940
pethidine1942
Tridione1944
amidone1946
meperidine1947
methadone1947
Physeptone1947
Butazolidin1951
phenylbutazone1952
opioid1955
Panadol1955
propoxyphene1955
Tylenol1956
acetaminophen1957
paracetamol1957
Distalgesic1958
oxycodone1958
Sernyl1958
morphinomimetic1959
phencyclidine1959
levorphanol1960
mefenamic acid1962
pentazocine1964
Talwin1965
ibuprofen1967
nalbuphine1969
naproxen1971
phy1971
Nurofen1982
the world > physical sensation > use of drugs and poison > an intoxicating drug > [noun] > a) narcotic drug(s) > opium > drug similar to opium
opiate?a1425
opioid1955
1955 E. G. Gross & M. J. Schiffrin Clin. Analgetics i. 4 Acheson and Pfeiffer have recently suggested that the term ‘opioid’ be used in lieu of ‘synthetic opiate-like compounds’.
1957 Pharmaceut. Jrnl. 179 321/1 Acheson has suggested that the morphinans and other synthetic morphine substitutes should be called opioids.
1974 M. C. Gerald Pharmacol. xiii. 237 Synthetic narcotic agents or opioids, which bear only highly subtle similarities to the structure of morphine.
1986 Fortune 18 Aug. 33/1 Among other things, opioids relieve pain and affect bowel activity. Some opioids found in the hypothalamus..also appear to stimulate appetite.
2017 R. J. Bonnie et al. Pain Managem. & Opioid Epidemic Introd. 17 Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States.
B. adj.
Of, relating to, or of the nature of an opioid.
ΘΚΠ
the world > health and disease > healing > medicines or physic > medicines for specific purpose > analgesic > [adjective]
anodyne1543
paregorical1651
paregoric1678
antalgic1753
pain-killing1865
analgetic1867
opioid1959
morphinomimetic1968
1959 Jrnl. Amer. Dental Assoc. Apr. 29/1 The doses and some of the side effects of the opiate and opioid drugs are compared.
1967 Pharmacol. Rev. 19 464 We have adopted the term opioid, which was proposed by Professor George H. Acheson, to designate those analgesics whose pattern of pharmacological and agonistic effects is similar to that of morphine and..have called this pattern of effects the opioid syndrome.
1976 H. W. Kosterlitz (title) Opiates and endogenous opioid peptides.
1981 Brain Res. Bull. 7 279 The prototype σ opioid receptor agonist N-allyl-normetazocine..was injected into the third cerebral ventricle of..cats.
2001 Esquire Aug. 117/2 Vicodin is not legally available in Britain, because such ‘opioid analgesics’ are classed as controlled drugs.
This entry has been updated (OED Third Edition, June 2004; most recently modified version published online March 2022).
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n.adj.1955
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