omeprazolen.

Brit.

/əʊˈmɛprəzəʊl/, U.S.

/oʊˈmɛprəˌzoʊl/

Origin: Formed within English, by compounding. Etymons: oxy- comb. form², methyl n., pyridine n., imidazole n., indole n.

Etymology: < o- (perhaps < oxy- comb. form²) + me- (perhaps < methyl n.) + pr- (perhaps < pyridine n.) + az- (in imidazole n.) + -ole (in indole n.).

Pharmacology.

A substituted benzimidazole which is a proton pump inhibitor and inhibits secretion of gastric acid, being given orally in the treatment of ulcers and gastro-oesophageal reflux; 5-methoxy-2-(4-methoxy-3,5-dimethyl-2-pyridylmethylsulfinyl)benzimidazole, C₁₇H₁₉N₃O₃S.Proprietary names for this drug include Losec and Prilosec.

ΚΠ

1981 WHO Chron. 35 Part 5. Suppl. List 46. 13 [Proposed International Nonproprietary Name] Omeprazole.

1988 Biochem. Pharmacol. 37 2543 Omeprazole, a known inhibitor of acid secretion, administered in vivo was found to bind specifically to the H⁺,K⁺-ATPase of the rabbit gastric mucosa.

1999 Sunday Mirror 10 Oct. (Personal section) 26/4 Treatment is aimed at reducing the acidity of the stomach's contents using drugs like cimetidine and omeprazole.

2001 Daily Tel. 14 Nov. 26/5 I have been diagnosed with a sliding hiatus hernia, with feelings of pressure in my throat and upper chest. I'm taking omeprazole—but are there alternative remedies?

This is a new entry (OED Third Edition, March 2004; most recently modified version published online March 2022).

单词	omeprazole
释义	omeprazolen. Brit. /əʊˈmɛprəzəʊl/, U.S. /oʊˈmɛprəˌzoʊl/ Origin: Formed within English, by compounding. Etymons: oxy- comb. form², methyl n., pyridine n., imidazole n., indole n. Etymology: < o- (perhaps < oxy- comb. form²) + me- (perhaps < methyl n.) + pr- (perhaps < pyridine n.) + az- (in imidazole n.) + -ole (in indole n.). Pharmacology. A substituted benzimidazole which is a proton pump inhibitor and inhibits secretion of gastric acid, being given orally in the treatment of ulcers and gastro-oesophageal reflux; 5-methoxy-2-(4-methoxy-3,5-dimethyl-2-pyridylmethylsulfinyl)benzimidazole, C₁₇H₁₉N₃O₃S.Proprietary names for this drug include Losec and Prilosec. ΚΠ 1981 WHO Chron. 35 Part 5. Suppl. List 46. 13 [Proposed International Nonproprietary Name] Omeprazole. 1988 Biochem. Pharmacol. 37 2543 Omeprazole, a known inhibitor of acid secretion, administered in vivo was found to bind specifically to the H⁺,K⁺-ATPase of the rabbit gastric mucosa. 1999 Sunday Mirror 10 Oct. (Personal section) 26/4 Treatment is aimed at reducing the acidity of the stomach's contents using drugs like cimetidine and omeprazole. 2001 Daily Tel. 14 Nov. 26/5 I have been diagnosed with a sliding hiatus hernia, with feelings of pressure in my throat and upper chest. I'm taking omeprazole—but are there alternative remedies? This is a new entry (OED Third Edition, March 2004; most recently modified version published online March 2022). < n.1981
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