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单词 norethynodrel
释义

norethynodreln.

Brit. /ˌnɔːrɛˈθʌɪnədrɛl/, U.S. /ˌnɔrəˈθaɪnoʊˌdrɛl/
Forms: 1900s– norethynodrel, 1900s– noretynodrel.
Origin: Formed wihtin English, by derivation. Etymons: nor- prefix, ethynyl n., English -odrel.
Etymology: < nor- prefix + ethyn- (in ethynyl n.) + -odrel, of unknown origin. O.E.D. Suppl. (1976) gives the pronunciation as (nǭreþi·nŏdrėl) /nɔːrɛˈθɪnədrɪl/.
Pharmacology.
A synthetic steroid hormone with actions similar to those of progesterone, used chiefly in combination with oestrogen in oral contraceptives; (17α)-17-hydroxy-19-norpregn-5(10)-en-20-yn-3-one, C20H26O2.Noretynodrel is the Recommended International Nonproprietary Name (rINN) of the compound (see quot. 1998).
ΘΚΠ
the world > health and disease > healing > medicines or physic > medical preparations of specific origin > hormones and substances with same effect > [noun]
epinephrine1899
pituitrin1909
oxytocin1927
Pitocin1929
Pitressin1929
progestin1930
progesterone1935
methyltestosterone1936
pregnenolone1936
hexœstrol1939
stilboestrol1939
hydroxyprogesterone1941
progestogen1941
Premarin1942
hydroxycorticosterone1943
gestagen1948
hydrocortisone1951
cortisol1953
fluorohydrocortisone1954
isophane1954
prednisolone1955
prednisone1955
norethisterone1956
norethynodrel1957
dexamethasone1958
fludrocortisone1958
norethindrone1960
antidiuretic hormone1961
medroxyprogesterone1962
Pergonal1963
mesterolone1965
norgestrel1966
quinestrol1966
pancuronium1967
pentagastrin1967
levonorgestrel1977
the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations for treating specific parts > [noun] > for the womb > specific drugs
norethisterone1956
norethynodrel1957
mestranol1962
1957 Endocrinology 60 804 Norethynodrel has been examined for its ability to produce endometrial gland development in the estrogen-primed spayed or immature rabbit.
1970 R. Passmore & J. S. Robson Compan. Med. Stud. II. xii. 6/1 Shift of the double bond in the A ring of norethisterone from the 4–5 to the 5–10 position produces the isomer, norethynodrel.
1993 N.Y. Rev. Bks. 23 Sept. 66/1 It had begun in 1960, with FDA's approval of G.D. Searle & Company's Enovid, in which the progestogen was norethynodrel.
1998 Brit. Approved Names 1997 (Brit. Pharmacopoeia Comm.) Suppl. iv. 17 The following names are changed... Change: norethynodrel... To: noretynodrel.
This entry has been updated (OED Third Edition, December 2003; most recently modified version published online March 2022).
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n.1957
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