notatinn.

Brit.

/nəʊˈteɪtɪn/, U.S.

/noʊˈteɪd(ə)n/

Origin: A borrowing from Latin, combined with an English element. Etymons: Latin notatum , -in suffix¹.

Etymology: < scientific Latin notatum, specific epithet (of Penicillium notatum) ( < classical Latin notātum , neuter of notātus : see notate adj.) + -in suffix¹.

Biochemistry. Now rare.

The enzyme glucose oxidase, a flavoprotein which catalyses the oxidation of glucose to d-glucono-δ-lactone and hydrogen peroxide, and which is produced by various microfungi (esp. Penicillium species).Glucose oxidase has some antibacterial activity (because of the generation of hydrogen peroxide), but is used chiefly in assays of glucose levels.

ΚΠ

1942 C. E. Coulthard et al. in Nature 28 Nov. 634/2 When a selected strain of Penicillium notatum Westling is grown on a Czapek-Dox medium an anti-bacterial substance is produced which differs in the majority of its properties from penicillin. This anti-bacterial substance was originally named ‘Penicillin A’, but in order to avoid confusion with penicillin we now prefer the name ‘notatin’.

1954 A. White et al. Princ. Biochem. xii. 264 A curious example of an antibiotic isolated from the mold Penicillium notatum is the substance notatin, which was later found to be the enzyme glucose oxidase containing flavin adenine dinucleotide.

1963 R. Bentley in P. D. Boyer et al. Enzymes (ed. 2) VII. xxiv. 569 Much of the work..has been carried out with purified preparations of notatin, and an unqualified reference to glucose oxidase in the rest of this chapter will indicate notatin.

1966 Science 27 May 1270/1 Keilin and Hartree demonstrated that preparations of glucose oxidase contain a second enzyme (which they name mutarotase) that accelerates the action of notatin by converting α-glucose to the beta form.

This entry has been updated (OED Third Edition, December 2003; most recently modified version published online March 2022).

单词	notatin
释义	notatinn. Brit. /nəʊˈteɪtɪn/, U.S. /noʊˈteɪd(ə)n/ Origin: A borrowing from Latin, combined with an English element. Etymons: Latin notatum , -in suffix¹. Etymology: < scientific Latin notatum, specific epithet (of Penicillium notatum) ( < classical Latin notātum , neuter of notātus : see notate adj.) + -in suffix¹. Biochemistry. Now rare. The enzyme glucose oxidase, a flavoprotein which catalyses the oxidation of glucose to d-glucono-δ-lactone and hydrogen peroxide, and which is produced by various microfungi (esp. Penicillium species).Glucose oxidase has some antibacterial activity (because of the generation of hydrogen peroxide), but is used chiefly in assays of glucose levels. ΚΠ 1942 C. E. Coulthard et al. in Nature 28 Nov. 634/2 When a selected strain of Penicillium notatum Westling is grown on a Czapek-Dox medium an anti-bacterial substance is produced which differs in the majority of its properties from penicillin. This anti-bacterial substance was originally named ‘Penicillin A’, but in order to avoid confusion with penicillin we now prefer the name ‘notatin’. 1954 A. White et al. Princ. Biochem. xii. 264 A curious example of an antibiotic isolated from the mold Penicillium notatum is the substance notatin, which was later found to be the enzyme glucose oxidase containing flavin adenine dinucleotide. 1963 R. Bentley in P. D. Boyer et al. Enzymes (ed. 2) VII. xxiv. 569 Much of the work..has been carried out with purified preparations of notatin, and an unqualified reference to glucose oxidase in the rest of this chapter will indicate notatin. 1966 Science 27 May 1270/1 Keilin and Hartree demonstrated that preparations of glucose oxidase contain a second enzyme (which they name mutarotase) that accelerates the action of notatin by converting α-glucose to the beta form. This entry has been updated (OED Third Edition, December 2003; most recently modified version published online March 2022). < n.1942
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