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单词 nucleosomal
释义

nucleosomaladj.

Brit. /ˌnjuːklɪəˈsəʊml/, U.S. /ˈˌn(j)uklioʊˈsoʊm(ə)l/
Origin: Formed within English, by derivation. Etymons: nucleosome n., -al suffix1.
Etymology: < nucleosome n. + -al suffix1.
Cell Biology.
Of or relating to a nucleosome or nucleosomes.
ΘΚΠ
the world > life > biology > biological processes > genetic activity > genetic components > [adjective] > DNA or RNA > of parts of DNA
sense1958
redundant1962
nucleosomal1975
antisense1977
1975 P. Oudet et al. in Cell 4 289/1 The chromatin fibre appears to be a self-assembling structure, since the nucleosomal arrangement can be reconstituted in vitro from DNA and the four histones.
1988 Biochemistry 27 5635/1 The forces that bind double-stranded DNA to the core-histone octamer to form nucleosomal particles appear to be essentially electrostatic.
2002 Jrnl. Biol. Chem. (Electronic ed.) 276 40621 Specific DNA-binding proteins..result in nucleosomal disruption or remodeling surrounding the promoter region, which then allows..general transcription machinery to activate transcription.
This entry has been updated (OED Third Edition, December 2003; most recently modified version published online March 2022).
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adj.1975
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