nucleoskeletonn.
/ˈnjuːklɪə(ʊ)ˌskɛlᵻt(ə)n/, U.S. /ˈˌn(j)uklioʊˈskɛlətn/, /ˈˌn(j)uklioʊˈskɛlədən/ Cell Biology.
The structural framework of the cell nucleus, consisting of a network of proteins and nucleic acid.
ΚΠ
1978 Jrnl. Cell Sci. 32 249 It seems reaonable to propose that this non-membranous layer..could correspond to a structural nuclear framework or ‘skeleton’ which confines and possibly organizes the interphase nuclear chromatin.]
1978 T. Cavalier-Smith in Jrnl. Cell Sci. 34 253 I suggest that DNA acts as a nucleoskeleton determining the volume of the nucleus.
1982 Jrnl. Biol. Chem. 257 3905 The nucleoskeleton, a macromolecular complex whose major structural elements are DNA and protein, is purported to be at least in part responsible for the gross morphology of the nucleus.
1988 Proc. National Acad. Sci. U.S.A. 85 8795/1 N-myristoylated proteins are found in numerous cellular compartments including plasma membrane, endoplasmic reticulum, nucleoskeleton, and cytosol.
2001 Exper. Cell Res. 264 201 Our data suggest that the nucleoskeleton is a permanent structure of the cell nucleus regardless of the nuclear transcriptional state.
This is a new entry (OED Third Edition, December 2003; most recently modified version published online March 2022).
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n.1978