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单词 nucleolin
释义

nucleolinn.1adj.

Brit. /ˌnjuːklɪˈəʊlɪn/, /njuːˈklɪəlɪn/, U.S. /n(j)uˈkliəl(ə)n/
Forms: 1800s nucleoline, 1900s– nucleolin.
Origin: A variant or alteration of another lexical item. Etymon: nucleolinus n.
Etymology: < nucleolinus n.; compare -in suffix2.With form nucleoline compare -ine suffix4.
Biology. rare (now disused).
A. n.1
= nucleolinus n.
ΘΚΠ
the world > life > biology > substance > cell > cell organelle or contents > [noun] > nucleus > nucleolus or paranucleus > parts of nucleolus
nucleolinus1869
nucleolin1890
nucleolonema1951
1890 Cent. Dict. Nucleoline, a nucleolinus.
1905 J. McCabe tr. E. Haeckel Evol. Man I. vi. 112 We find in many ova..a still further point within the germinal spot, a ‘nucleolin’ [Ger. Nucleolinus (1874)], which goes by the name of the germinal point.
B. adj.
Of or relating to a nucleolinus. Obsolete.
ΚΠ
1890 Cent. Dict. Nucleoline, of or pertaining to a nucleolinus.
This entry has been updated (OED Third Edition, December 2003; most recently modified version published online March 2022).

nucleolinn.2

Brit. /ˌnjuːklɪˈəʊlɪn/, /njuːˈklɪəlɪn/, U.S. /n(j)uˈkliəl(ə)n/
Origin: Formed within English, by derivation. Etymons: nucleolus n., -in suffix1.
Etymology: < nucleolus n. + -in suffix1.
Biochemistry.
1. gen. The substance of which nucleoli are formed. Now disused.
ΚΠ
1906 E. Dale in Philos. Trans. (Royal Soc.) B. 198 245 In some nucleoli there are one or more granules which stain still more deeply than the surrounding nucleolin.
1943 Bot. Gaz. 104 645/2 Whether the nucleolar staining method of Semmens and Bhaduri..actually satisfies the technician's demand for a definite and specific stain for nucleolin, to go with the only definite and specific stain for chromatin.., is a matter for the test of time and expert consideration.
2. spec. A protein found abundantly in the nucleoli of cells, associated with the transcription of ribosomal RNA and the assembly of ribosomes.
ΚΠ
1987 Proc. National Acad. Sci. U.S.A. 84 1472 (title) Nucleolin, the major nucleolar protein of growing eukaryotic cells: An unusual protein structure revealed by the nucleotide sequence.
1989 B. Alberts et al. Molecular Biol. Cell (ed. 2) ix. 541 An especially notable component is nucleolin, an abundant, well-characterized RNA-binding protein that seems to coat only ribosomal transcripts.
1994 Science 29 July 617/3 Spectroscopic analysis and molecular modelling of nucleolin RGGF repeats predict a helical β-spiral structure.
This is a new entry (OED Third Edition, December 2003; most recently modified version published online March 2022).
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n.1adj.1890n.21906
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