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单词 nonactin
释义

nonactinn.

Brit. /nɒnˈaktɪn/, U.S. /nɑnˈækt(ə)n/
Origin: A borrowing from German. Etymon: German Nonactin.
Etymology: < German Nonactin (R. Corbaz et al. 1955, in Helvetica Chimica Acta 38 1445) < non- non- prefix + Actin- (in Actinomycetes actinomycetes n.), with allusion to Aktion action n. (with reference to its initial failure to exhibit antibiotic activity).
Biochemistry and Pharmacology.
A macrolide compound produced by Streptomyces griseus, C40H64O12, which has antibiotic activity but is used chiefly as an experimental ionophore.
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the world > health and disease > healing > medicines or physic > medicines for specific purpose > antibiotics > [noun] > other antibiotics
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fumigatin1938
M and B1938
gramicidin1940
tyrocidine1940
tyrothricin1940
clavacin1942
fumigacin1942
streptothricin1942
aspergillic acid1943
aspergillin1943
clavatin1943
helvolic acid1943
streptomycin1944
subtilin1944
bacitracin1945
viridin1945
javanicin1946
nisin1947
nitrofurazone1947
polymyxin1947
aureomycin1948
chloramphenicol1949
clitocybin1949
neomycin1949
Terramycin1950
viomycin1950
cephalosporin1951
fumagillin1951
nigericin1951
achromycin1952
carbomycin1952
erythromycin1952
nystatin1952
oxytetracycline1952
tetracycline1952
chlortetracycline1953
nitrofurantoin1953
oligomycin1953
puromycin1953
bacteriocin1954
albomycin1955
spiramycin1955
valinomycin1955
amphotericin B1956
mitomycin1956
novobiocin1956
oleandomycin1956
paromomycin1956
vancomycin1956
kanamycin1957
macrolide1957
ristocetin1957
streptovaricin1957
ethionamide1959
rifamycin1959
strep1959
mithramycin1960
fucidin1961
virginiamycin1961
cephalothin1962
fusidic acid1962
nonactin1962
trimethoprim1962
daunomycin1963
lincomycin1963
anthracycline1964
cephaloridine1964
spectinomycin1964
doxycycline1966
rifampicin1966
minocycline1967
rifampin1968
Adriamycin1969
daunorubicin1969
ribostamycin1970
doxorubicin1971
tobramycin1971
milbemycin1975
fluoroquinolone1984
1962 Helvetica Chimica Acta 45 138 The neutral, colourless and optically inactive metabolite nonactin, C40H64O12, obtained from cultures of several Actinomyces strains, is a macrocyclic tetralactone.
1969 New Scientist 31 July 225/3 Nonactin..wraps itself like a ball around a central potassium ion, pointing eight atoms at it, as if from the vertices of a cube.
2000 Jrnl. Gen. Physiol. 115 571 We have used the well-studied conductance probes nonactin, alamethicin, and tetraphenylborate to investigate how annexins alter the functional properties of planar lipid bilayers.
This is a new entry (OED Third Edition, December 2003; most recently modified version published online March 2022).
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n.1962
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