1768 (Royal Soc.) 57 435 To swallow it, digest it, and return the non-nutritive parts back again by the same way.
1898 26 36 Glycerin is a non-nutritive substance for the moss-spores.
1983 M. G. Lindley in T. H. Grenby et al. viii. 240 Non-nutritive sweeteners in carbonated beverages need to be carefully selected for flavour.