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单词 nesidioblast
释义

nesidioblastn.

Brit. /nᵻˈsɪdɪə(ʊ)ˌblast/, /nᵻˈsɪdɪə(ʊ)ˌblɑːst/, U.S. /nəˈsɪdɪoʊˌblæst/
Origin: A borrowing from Greek, combined with an English element. Etymons: Greek νησίδιον , -blast comb. form.
Etymology: < ancient Greek νησίδιον islet ( < νῆσος island, of unknown origin + -ίδιον -idium comb. form) + -blast comb. form.
Histology and Physiology.
An immature precursor of the insulin-producing cell of the islets of Langerhans.
ΚΠ
1938 G. F. Laidlaw in Amer. Jrnl. Pathol. 14 131 The cells that differentiate out of the duct epithelium to build islets may be called nesidioblasts—islet builders.
1981 R. N. Hardy Endocrine Physiol. iv. 36 In adults, primary insulin-secreting tumours of the pancreas (insulinomas) may develop and a diffuse proliferation of β-cell precursors (nesidioblasts) has been described in babies.
1997 Clin. Endocrinol. 47 245 Insulin expression was observed in both the islets and also the isolated nesidioblasts.
This is a new entry (OED Third Edition, September 2003; most recently modified version published online March 2022).
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n.1938
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