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单词 nerve growth factor
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nerve growth factor
nerve growth factor n. (a) a polypeptide consisting in its active form of two identical chains of 120 amino acids, which is produced normally by neurons, Schwann cells, glial cells, and various types of epithelial and connective tissue cells, and promotes the growth of (esp. sensory and sympathetic) neurons and neurites, and also has certain modulatory effects on the immune system (abbreviated NGF); (b) any of various other polypeptides that promote the growth and maintenance of neurons.
ΚΠ
1954 S. Cohen et al. in Proc. National Acad. Sci. U.S.A. 40 1014 (title) A nerve growth-stimulating factor isolated from sarcomas 37 and 180.]
1958 Science 12 Sept. 602/2 A study of the formation of nerve fibers by tissue-cultured cells under the influence of the nerve-growth factor.
1994 N.Y. Times 8 Mar. c3/5 The hormone [sc. estrogen] could exert its influence by making neurons more sensitive to the stimulus of nerve growth factor.
1997 New Scientist 31 May 18/1 They then used antibodies to selectively switch off two nerve growth factors, brain-derived neurotrophic factor (BDNF) and neurotropin-3 (NT-3), in the tissue.
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