nephrotoxicityn.

Brit.

/ˌnɛfrə(ʊ)tɒkˈsɪsᵻti/, U.S.

/ˈˌnɛfroʊˌtɑkˈsɪsᵻdi/

Origin: Formed within English, by compounding. Etymons: nephro- comb. form, toxicity n.

Etymology: < nephro- comb. form + toxicity n., after nephrotoxic adj.

Medicine.

Toxicity to the kidneys; an instance or type of this. Also: the degree to which a drug or other substance is nephrotoxic.

ΘΚΠ

the world > physical sensation > use of drugs and poison > poison > [noun] > quality of being poisonous > specific

fungitoxicity1945

hepatotoxicity1952

nephrotoxicity1957

embryotoxicity1964

mycotoxicity1969

genotoxicity1978

the world > health and disease > ill health > a disease > disorders of internal organs > glandular disorders > [noun] > disorders of kidneys > toxic effect on

nephrotoxicity1957

1957 Amer. Jrnl. Pathol. 33 895 (title) Studies on the nephrotoxicity of 5-hydroxytryptamine.

1961 Lancet 22 July 179/1 The new preparation..appeared..to be devoid of..nephrotoxicity.

1970 R. Passmore & J. S. Robson Compan. Med. Stud. II. xxxii. 4/2 Mercury poisoning is the oldest and best understood type of nephrotoxicity.

1989 J. A. B. Collier & J. M. Longmore Oxf. Handbk. Clin. Specialties (ed. 2) iv. 354 If levels are progressively rising, suspect progressive nephrotoxicity.

1992 Toxicol. Pathol. 20 608 This reduction followed the known in vivo nephrotoxicities of the aminoglycosides streptomycin, gentamicin, and neomycin.

2001 Hospital Doctor 15 Mar. 27/3 The following serious adverse effects have been reported in association with the use of NSAIDs and cannot be ruled out for rofecoxib: nephrotoxicity including interstitial nephritis and nephrotic syndrome.

This entry has been updated (OED Third Edition, September 2003; most recently modified version published online March 2022).

单词	nephrotoxicity
释义	nephrotoxicityn. Brit. /ˌnɛfrə(ʊ)tɒkˈsɪsᵻti/, U.S. /ˈˌnɛfroʊˌtɑkˈsɪsᵻdi/ Origin: Formed within English, by compounding. Etymons: nephro- comb. form, toxicity n. Etymology: < nephro- comb. form + toxicity n., after nephrotoxic adj. Medicine. Toxicity to the kidneys; an instance or type of this. Also: the degree to which a drug or other substance is nephrotoxic. ΘΚΠ the world > physical sensation > use of drugs and poison > poison > [noun] > quality of being poisonous > specific fungitoxicity1945 hepatotoxicity1952 nephrotoxicity1957 embryotoxicity1964 mycotoxicity1969 genotoxicity1978 the world > health and disease > ill health > a disease > disorders of internal organs > glandular disorders > [noun] > disorders of kidneys > toxic effect on nephrotoxicity1957 1957 Amer. Jrnl. Pathol. 33 895 (title) Studies on the nephrotoxicity of 5-hydroxytryptamine. 1961 Lancet 22 July 179/1 The new preparation..appeared..to be devoid of..nephrotoxicity. 1970 R. Passmore & J. S. Robson Compan. Med. Stud. II. xxxii. 4/2 Mercury poisoning is the oldest and best understood type of nephrotoxicity. 1989 J. A. B. Collier & J. M. Longmore Oxf. Handbk. Clin. Specialties (ed. 2) iv. 354 If levels are progressively rising, suspect progressive nephrotoxicity. 1992 Toxicol. Pathol. 20 608 This reduction followed the known in vivo nephrotoxicities of the aminoglycosides streptomycin, gentamicin, and neomycin. 2001 Hospital Doctor 15 Mar. 27/3 The following serious adverse effects have been reported in association with the use of NSAIDs and cannot be ruled out for rofecoxib: nephrotoxicity including interstitial nephritis and nephrotic syndrome. This entry has been updated (OED Third Edition, September 2003; most recently modified version published online March 2022). < n.1957
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