单词 | neurotropic |
释义 | neurotropicadj. 1. Chiefly Pathology. Having an affinity for or attraction to neural tissue; tending to infect or affect the nervous system preferentially. ΘΚΠ the world > health and disease > ill health > a disease > disorders of internal organs > disorders of nervous system > [adjective] > tendency towards neurotropic1900 1900 tr. P. Ehrlich in Proc. Royal Soc. 66 431 A very great number of other chemical substances, narcotics, alkaloids, and other neurotropic bodies, were not in a position to withdraw the toxine once deposited in the central nervous system. 1909 Proc. Royal Soc. B. 81 126 This dye [sc. methylene blue], though neurotropic, is not monotropic. 1922 Med. Jrnl. Austral. ii. 261/2 Vaccinia is the least neurotropic, while poliomyelitis is the most exclusively neurotropic. 1939 Lancet 4 Mar. 497/1 (title) A neurotropic strain of human influenza virus. 1961 R. D. Baker Essent. Pathol. viii. 136 Venoms of snakes are hemolytic or neurotropic. 1973 Nature 26 Jan. 247/1 The MV strain of [poliomyelitis] virus..was then shown to be so adapted to monkey brain passage and so neurotropic that it would no longer grow in cells from other organs. 1987 D. J. Weatherall et al. Oxf. Textbk. Med. (ed. 2) I. v. 555/2 The parasites are neurotropic, both in men and rats, and so migrate to the brain. 2. Physiology. Directing the growth of neurons or neurites; of, relating to, or producing neurotropism. ΘΚΠ the world > life > biology > biological processes > action of nervous system > [adjective] nervo-vital1843 neural1864 neurotrophic1887 neurotropic1909 1909 D. Orr & R. G. Rows tr. E. Lugaro Mod. Problems Psychiatry vi. 95 Intermediary chemotropic mechanisms intervene..leaving to more particular neurotropic affinities the further task of establishing the closest and most definite connections. 1912 Jrnl. Nerv. & Mental Dis. 39 774 Is the comparative incapacity of the nervous system to regenerate due to some incapacity of the mechanical obstacles, absence of preestablished routes, or to some peculiar defect in the Schwann cells, the chief if not the only elaborators of neurotrophic [sic] material? 1928 R. M. May tr. S. Ramón y Cajal Degeneration & Regeneration Nerv. Syst. I. 374 This fact bears out the view that the neurotropic material is an enzyme segregated by the living cells, instead of a product of the decomposition or disintegration of the nervous tissue. 1968 A. F. W. Hughes Aspects Neural Ontogeny i. 33 For Ramon y Cajal the association of a regenerating fibre with the bands of Büngner was an instance of neurotropic attraction. 1968 S. Sunderland Nerves & Nerve Injuries xxxii. 405 Whether or not the tissues of the distal stump exert a neurotropic influence on the regenerating process..is still unsettled. 1992 Lancet 27 June 1592/1 Any number of neurotropic factors will not compensate for a surgeon's lack of knowledge or skill. This entry has been updated (OED Third Edition, September 2003; most recently modified version published online March 2022). < |
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