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单词 nifurtimox
释义

nifurtimoxn.

Brit. /nʌɪˈfəːtᵻmɒks/, U.S. /ˌnaɪˈfərdəˌmɑks/
Origin: Probably formed within English, by compounding. Etymons: nitro- comb. form, nitro- comb. form, oxide n.
Etymology: Probably < ni- (in nitro- comb. form) + fur- (in furan n.) + -tim- (of unknown origin) + ox- (in oxide n.).
Pharmacology.
An antitrypanosomal drug administered orally in the treatment of Chagas' disease; C10H13N3O5S.
ΘΚΠ
the world > health and disease > healing > medicines or physic > medicines for specific purpose > remedies for parasitic infections > [noun] > other internal parasiticides
trypanosomacide1903
trypanocide1917
schizonticide1943
ethidium bromide1952
schistosomicide1954
nifurtimox1969
1969 Approved Names (Brit. Pharmacopœia Comm.) 46 Nifurtimox..(Treatment of trypanosomiasis).
1978 Nature 22 June 627/2 The lack of an active and specific drug against Trypanosoma cruzi is..one of the best known facts about Chagas' disease. The only compound mentioned in the WHO list is a nitrofurilidone derivative, nifurtimox..effective in the acute stage of the disease.
1991 New Scientist 19 Oct. 16/2 Chagas disease has left millions of South Americans crippled by heart disease and other chronic disorders... There are two drugs, benznidazole and nifurtimox, which are thought to cure up to 70 per cent of cases of infection.
This is a new entry (OED Third Edition, September 2003; most recently modified version published online March 2022).
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n.1969
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