| 单词 | neuroleptic malignant syndrome |
| 释义 | > as lemmasneuroleptic malignant syndrome neuroleptic malignant syndrome n. a rare, sometimes fatal, complication of neuroleptic drug treatment, characterized by hyperthermia, muscle rigidity, and altered autonomic function and consciousness. ΚΠ 1968 J. Delay & P. Deniker in P. J. Vinken & G. W. Bruyn Dis. Basal Ganglia 258/2 The neuroleptic ‘malignant’ syndrome. It is important to remind ourselves of the most serious but also the rarest and least known of the complications of neuroleptic chemotherapy, that is, the ‘malignant’ syndrome of pallor and hyperthermia. 1989 Western Jrnl. Med. (Nexis) 151 326 Although the pathogenesis of the neuroleptic malignant syndrome remains unclear, it has been proposed that a rapid blockade of postsynaptic dopamine receptors by large doses of neuroleptic drugs and a hypothalamic disease may underlie this disorder. 1996 Pulse 20 Apr. 42 (advt.) C-I, warnings, etc... Extrapyramidal symptoms and the neuroleptic malignant syndrome (NMS) may occur with both monotherapy and concurrent neuroleptics. < as lemmas |
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