| 单词 | neurofibrillary tangle |
| 释义 | > as lemmasneurofibrillary tangle neurofibrillary tangle n. Pathology an accumulation of twisted and distorted neurofibrils found within neurons, esp. as a feature of Alzheimer's disease and certain other neurological disorders. ΚΠ 1963 Jrnl. Neuropathol. & Exper. Neurol. 22 629 The neurofibrillary tangle of Alzheimer is one of the most distinctive cytopathologic changes that occur in the central nervous system. 1988 New Scientist 12 Nov. 46/1 Neurofibrillary tangles are bundles of twisted filaments that accumulate within brain cells. 1996 O. Sacks Island of Colour-blind ii. 189 The monkeys developed no clinical symptoms in the four years of the trial, but autopsies showed many neurofibrillary tangles, as well as degenerative changes in the motor neurons. < as lemmas |
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