nickasen.
/ˈnɪkeɪz/, U.S. /ˈnɪkeɪz/, /ˈnɪkeɪs/ Biochemistry.
Any enzyme capable of making a nick in one strand of a double-stranded DNA molecule; a nicking enzyme. Cf. nick n.1 2i.
ΘΚΠ
the world > life > biology > biological processes > genetic activity > genetic components > [noun] > nucleic acid > enzymes
galactase1898
cellulase1901
nuclease1902
xanthine oxidase1905
exoenzyme1908
glucosidase1909
galactase1910
nucleosidase1911
nucleotidase1911
adenosine deaminase1913
cellobiase1919
hydratase1922
activase1928
hexokinase1930
histaminase1930
kallikrein1930
Michaelis constant1930
cholinesterase1932
phosphodiesterase1932
chymotrypsin1933
glycosidase1933
rhodanese1933
acetylcholinesterase1937
prolidase1937
diaphorase1938
aconitase1939
hyaluronidase1940
transaminase1940
hydrase1943
isomerase1943
lactoperoxidase1943
streptokinase1944
pectinesterase1945
pectinmethylesterase1945
phosphokinase1946
alliinase1947
CoA1947
phosphotransferase1948
polymerase1948
transferase1948
elastase1949
amyloglucosidase1950
transacetylase1950
transhydrogenase1952
hydroxylase1953
kinase1953
transketolase1953
synthase1954
hexosaminidase1955
translocase1957
angiotensinase1958
angiotensin converting enzyme1960
photoenzyme1960
acetyltransferase1961
adenyl cyclase1961
adenylate cyclase1962
replicase1962
ADA1963
transcriptase1963
adenylyl cyclase1964
recombinase1964
laminarinase1966
nickase1967
acrosin1970
reverse transcriptase1970
cellobiohydrolase1972
cyclooxygenase1974
laminaranase1974
primase1977
helicase1978
monodeiodinase1978
transposase1979
maturase1980
1967 A. W. Kozinski & Z. Z. Felgenhauer in Jrnl. Virol. 1 1193/2 ..It was inferred that these steps are due to enzymes which were designated, according to their functions, ‘nickase’ and ‘repairase’.
1987 Jrnl. Bacteriol. 169 4901 (title) LiCl treatment releases a nickase implicated in genetic transformation of Streptococcus pneumoniae.
1995 Virology 209 131/2 The mutations were directed at two particular motifs predicted to constitute the catalytic domain of the nickase.
This is a new entry (OED Third Edition, September 2003; most recently modified version published online March 2022).
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n.1967