单词 | mustine |
释义 | mustinen. Medicine. A compound with strong cytotoxic properties, given intravenously (usually as the hydrochloride) in the treatment of Hodgkin's disease and some other neoplasms. Also mustine hydrochloride.Mustine is a nitrogen mustard. Chemical name: bis(2-chloroethyl)methylamine, (ClCH2CH2)2NCH3. ΚΠ 1952 Martindale's Extra Pharmacopœia (ed. 23) I. 731 The action of mustine hydrochloride is similar to that of irradiation, but the effect is exerted more rapidly and is more severe. 1974 R. M. Kirk et al. Surgery iv. 60 Nitrogen mustards including mustine, are related to the offensive war games. 1996 D. J. Weatherall et al. Oxf. Textbk. Med. (ed. 3) III. xxii. 3574/2 Mustine is powerfully emetogenic, induces sterility (especially in males), and may be associated with a higher risk of stem-cell damage. This is a new entry (OED Third Edition, June 2003; most recently modified version published online March 2022). < n.1952 |
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