nalidixicadj.

Brit.

/nalᵻˈdɪksɪk/, U.S.

/ˈˌnæləˈdɪksɪk/

Origin: Formed within English, by compounding. Etymons: naphthyridine n., carboxylic adj., dihydro- comb. form.

Etymology: < na- (in naphthyridine n.) + -li- (perhaps representing carboxylic adj.) + -di- (in dihydro- comb. form) + -xic (perhaps representing carboxylic adj.), elements in the chemical name.

Pharmacology.

nalidixic acid n. a bicyclic pyridine derivative used as an antiseptic which inhibits bacterial reproduction, given orally in the treatment of infections of the urinary tract; 1-ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid, C₁₂H₁₂N₂O₃.

ΘΚΠ

the world > health and disease > healing > medicines or physic > medicines for specific purpose > antiseptic > [noun] > specific

naphthalene1821

carbolic acid1835

creosote1835

Sanitas1878

chlorocresol1886

salol1887

Listerine1889

salufer1894

Airol1895

fluorol1895

thymoform1899

xeroform1901

triformol1907

thymoloform1911

hexamine1914

Eusol1915

flavine1917

proflavine1917

Dakin1920

naphtha1920

methenamine1926

T.C.P.1934

Zephiran1935

leptazol1946

cetrimide1948

nalidixic acid1962

clioquinol1967

crystal violet1996

1962 Jrnl. Medicinal & Pharmaceut. Chem. 5 1064 The antibacterial activity of nalidixic acid has been demonstrated against a variety of microorganisms causing disease in man and animals.

1976 Nature 15 Apr. 643/1 Nalidixic acid (NAL) has been described as a specific inhibitor of bacterial DNA synthesis in vivo and in vitro.

1998 Economist 4 Apr. 120/3 They looked at seven strains in all—three with resistance to the antibiotic streptomycin and two for each of rifampicin and nalidixic acid.

This entry has been updated (OED Third Edition, June 2003; most recently modified version published online March 2022).

单词	nalidixic
释义	nalidixicadj. Brit. /nalᵻˈdɪksɪk/, U.S. /ˈˌnæləˈdɪksɪk/ Origin: Formed within English, by compounding. Etymons: naphthyridine n., carboxylic adj., dihydro- comb. form. Etymology: < na- (in naphthyridine n.) + -li- (perhaps representing carboxylic adj.) + -di- (in dihydro- comb. form) + -xic (perhaps representing carboxylic adj.), elements in the chemical name. Pharmacology. nalidixic acid n. a bicyclic pyridine derivative used as an antiseptic which inhibits bacterial reproduction, given orally in the treatment of infections of the urinary tract; 1-ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid, C₁₂H₁₂N₂O₃. ΘΚΠ the world > health and disease > healing > medicines or physic > medicines for specific purpose > antiseptic > [noun] > specific naphthalene1821 carbolic acid1835 creosote1835 Sanitas1878 chlorocresol1886 salol1887 Listerine1889 salufer1894 Airol1895 fluorol1895 thymoform1899 xeroform1901 triformol1907 thymoloform1911 hexamine1914 Eusol1915 flavine1917 proflavine1917 Dakin1920 naphtha1920 methenamine1926 T.C.P.1934 Zephiran1935 leptazol1946 cetrimide1948 nalidixic acid1962 clioquinol1967 crystal violet1996 1962 Jrnl. Medicinal & Pharmaceut. Chem. 5 1064 The antibacterial activity of nalidixic acid has been demonstrated against a variety of microorganisms causing disease in man and animals. 1976 Nature 15 Apr. 643/1 Nalidixic acid (NAL) has been described as a specific inhibitor of bacterial DNA synthesis in vivo and in vitro. 1998 Economist 4 Apr. 120/3 They looked at seven strains in all—three with resistance to the antibiotic streptomycin and two for each of rifampicin and nalidixic acid. This entry has been updated (OED Third Edition, June 2003; most recently modified version published online March 2022). < adj.1962
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