单词 | myelosuppression |
释义 | myelosuppressionn. Medicine. Inhibition of the normal activity of the bone marrow (reduced haematopoiesis), usually as a result of cytotoxic chemotherapy or radiotherapy. ΚΠ 1967 Ann. Internal Med. 67 1236/1 Bacterial endotoxin has been used to estimate the granulocyte reserves of patients receiving chemotherapeutic agents known to cause myelosuppression. 1975 Proc. National Acad. Sci. U.S.A. 72 3683/1 Regimens have been hampered by the occasional development of serious toxicities, such as neurologic sequelae, renal failure, and myelosuppression. 1987 M. J. Neal Med. Pharmacol. at Glance xxxiii. 73/2 It causes more myelosuppression than vincristine but is less neurotoxic. 2002 Cancer 94 1457 The most prominent Grade 3 and 4 toxicities were reversible myelosuppression and fatigue. This is a new entry (OED Third Edition, June 2003; most recently modified version published online March 2022). < n.1967 |
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