myelinotoxicadj.

Brit.

/ˌmʌɪᵻlɪnəˈtɒksɪk/, U.S.

/ˈˌmaɪələnoʊˈtɑksɪk/,

/ˌmaɪələnoʊˈtɑksɪk/

Origin: Formed within English, by compounding. Etymons: myelino- comb. form, toxic adj.

Etymology: < myelino- comb. form + toxic adj.

Medicine.

That damages or destroys myelin.

ΚΠ

1965 Ann. N.Y. Acad. Sci. 122 283 The salt-precipitated fractions of EAE sera demonstrate the myelinotoxic activity of the entire serum.

1975 Acta Neuropathologica 32 127 Slight myelinotoxic activity was present in 2 sera.

1998 Jrnl. Neurol., Neurosurg. & Psychiatry 65 23 Local factors or differential susceptibility between the central and peripheral nervous system may determine whether myelinotoxic or neurotoxic processes predominate.

2001 Neurology 56 1278 TNFα, a myelinotoxic factor, may be the major mediator.

This is a new entry (OED Third Edition, June 2003; most recently modified version published online March 2022).

单词	myelinotoxic
释义	myelinotoxicadj. Brit. /ˌmʌɪᵻlɪnəˈtɒksɪk/, U.S. /ˈˌmaɪələnoʊˈtɑksɪk/, /ˌmaɪələnoʊˈtɑksɪk/ Origin: Formed within English, by compounding. Etymons: myelino- comb. form, toxic adj. Etymology: < myelino- comb. form + toxic adj. Medicine. That damages or destroys myelin. ΚΠ 1965 Ann. N.Y. Acad. Sci. 122 283 The salt-precipitated fractions of EAE sera demonstrate the myelinotoxic activity of the entire serum. 1975 Acta Neuropathologica 32 127 Slight myelinotoxic activity was present in 2 sera. 1998 Jrnl. Neurol., Neurosurg. & Psychiatry 65 23 Local factors or differential susceptibility between the central and peripheral nervous system may determine whether myelinotoxic or neurotoxic processes predominate. 2001 Neurology 56 1278 TNFα, a myelinotoxic factor, may be the major mediator. This is a new entry (OED Third Edition, June 2003; most recently modified version published online March 2022). < adj.1965
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