multivesicularadj.

Brit.

/ˌmʌltɪvᵻˈsɪkjᵿlə/, U.S.

/ˌməltivəˈsɪkjələr/; see also multi- comb. form.

Origin: Formed within English, by compounding. Etymons: multi- comb. form, vesicular adj.

Etymology: < multi- comb. form + vesicular adj.

1. Cell Biology. Designating intracellular membranous structures consisting of a number of vesicles; spec. (esp. in multivesicular body) designating a type of endosome or lysosome consisting of a group of small vesicles contained within a limiting membrane.

ΚΠ

1957 Jrnl. Biophysical & Biochem. Cytol. 3 305 Multivesicular bodies were found in the central core [of the vitelline body of spider oocytes].

1974 V. B. Mountcastle et al. Med. Physiol. (ed. 13) I. xxvii. 707/1 (caption) Multivesicular reticular membrane.

1984 L. W. Browder Developmental Biol. (ed. 2) vii. 269 Endogenous yolk production occurs within structures called multivesicular bodies.

1993 European Jrnl. Cell Biol. 61 208 Spherical multivesicular bodies (MVBs) were the predominant endocytic compartments in HEp-2 cells.

2002 Traffic 3 87 The proenzyme was concentrated in dense cores within small vesicles and multivesicular endosomes.

2. Biology and Medicine. Containing many vesicles or cavities.

ΚΠ

1966 Jrnl. Ultrastruct. Res. 16 693 The fine structure of multivesicular cells with large microvilli in the epithelium of the mouse colon.

1983 Biochimica et Biophysica Acta 728 339 A novel type of liposome, named here multivesicular liposomes, was prepared by evaporation of organic solvents from chloroform-ether spherules suspended in water.

1986 Austral. & New Zealand Jrnl. Surg. 55 519 It [sc. Echinococcus multilocularis] produces clinically malignant multivesicular infiltrating lesions most often in the liver.

1994 Pharmaceutical Res. 11 1479 The internal structure of microparticles can be changed from a multivesicular to a matrix-like structure.

1999 Clin. Biochem. 32 579 There was a significant increase in the number and activity of multivesicular stellate cells in ALD [= alcoholic liver disease] patients.

2001 Infection 29 119 MRI may facilitate the diagnosis [of alveolar echinococcosis] in uncertain cases..by showing the characteristic multivesicular structure, necrotic areas and proximity to vascular structures.

3. Physiology. Designating or relating to the release of a neurotransmitter from more than one synaptic vesicle.

ΚΠ

1980 Acta Physiologica Scandinavica 109 363 (title) Possible role of nerve impulse induced sodium ion flux in a proposed multivesicular fractional release of adrenaline and noradrenaline from the chromaffin cell.

1983 Brain Res. 287 299 Recent observations of subminiature end-plate potentials..and of multimodal distribution of the MEPP amplitudes have led to the formulation of a new ‘multivesicular hypothesis’.

1994 European Jrnl. Neurosci. 6 1544 The pre- and postsynaptic origins of mIPSCs [= miniature inhibitory postsynaptic currents] amplitude fluctuations are discussed in the context of multivesicular release versus the hypothesis of postsynaptic receptor saturation.

2002 Nature Neurosci. 5 147 We propose that the ribbon synapse operates by multivesicular release, possibly to achieve high-frequency transmission.

This is a new entry (OED Third Edition, March 2003; most recently modified version published online March 2022).

单词	multivesicular
释义	multivesicularadj. Brit. /ˌmʌltɪvᵻˈsɪkjᵿlə/, U.S. /ˌməltivəˈsɪkjələr/; see also multi- comb. form. Origin: Formed within English, by compounding. Etymons: multi- comb. form, vesicular adj. Etymology: < multi- comb. form + vesicular adj. 1. Cell Biology. Designating intracellular membranous structures consisting of a number of vesicles; spec. (esp. in multivesicular body) designating a type of endosome or lysosome consisting of a group of small vesicles contained within a limiting membrane. ΚΠ 1957 Jrnl. Biophysical & Biochem. Cytol. 3 305 Multivesicular bodies were found in the central core [of the vitelline body of spider oocytes]. 1974 V. B. Mountcastle et al. Med. Physiol. (ed. 13) I. xxvii. 707/1 (caption) Multivesicular reticular membrane. 1984 L. W. Browder Developmental Biol. (ed. 2) vii. 269 Endogenous yolk production occurs within structures called multivesicular bodies. 1993 European Jrnl. Cell Biol. 61 208 Spherical multivesicular bodies (MVBs) were the predominant endocytic compartments in HEp-2 cells. 2002 Traffic 3 87 The proenzyme was concentrated in dense cores within small vesicles and multivesicular endosomes. 2. Biology and Medicine. Containing many vesicles or cavities. ΚΠ 1966 Jrnl. Ultrastruct. Res. 16 693 The fine structure of multivesicular cells with large microvilli in the epithelium of the mouse colon. 1983 Biochimica et Biophysica Acta 728 339 A novel type of liposome, named here multivesicular liposomes, was prepared by evaporation of organic solvents from chloroform-ether spherules suspended in water. 1986 Austral. & New Zealand Jrnl. Surg. 55 519 It [sc. Echinococcus multilocularis] produces clinically malignant multivesicular infiltrating lesions most often in the liver. 1994 Pharmaceutical Res. 11 1479 The internal structure of microparticles can be changed from a multivesicular to a matrix-like structure. 1999 Clin. Biochem. 32 579 There was a significant increase in the number and activity of multivesicular stellate cells in ALD [= alcoholic liver disease] patients. 2001 Infection 29 119 MRI may facilitate the diagnosis [of alveolar echinococcosis] in uncertain cases..by showing the characteristic multivesicular structure, necrotic areas and proximity to vascular structures. 3. Physiology. Designating or relating to the release of a neurotransmitter from more than one synaptic vesicle. ΚΠ 1980 Acta Physiologica Scandinavica 109 363 (title) Possible role of nerve impulse induced sodium ion flux in a proposed multivesicular fractional release of adrenaline and noradrenaline from the chromaffin cell. 1983 Brain Res. 287 299 Recent observations of subminiature end-plate potentials..and of multimodal distribution of the MEPP amplitudes have led to the formulation of a new ‘multivesicular hypothesis’. 1994 European Jrnl. Neurosci. 6 1544 The pre- and postsynaptic origins of mIPSCs [= miniature inhibitory postsynaptic currents] amplitude fluctuations are discussed in the context of multivesicular release versus the hypothesis of postsynaptic receptor saturation. 2002 Nature Neurosci. 5 147 We propose that the ribbon synapse operates by multivesicular release, possibly to achieve high-frequency transmission. This is a new entry (OED Third Edition, March 2003; most recently modified version published online March 2022). < adj.1957
随便看	centrolinead centrolineal centromere centromeres centromeric centron centronics centronote centroplasm centrosomal centrosome centrosomes centrosomic centrosphere centrospheres centrostaltic centrostomatous centrosymmetric centrosymmetrical centrosymmetry centrotylote centrum centrums centry cents