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单词 multimerize
释义

multimerizev.

Brit. /ˈmʌltᵻmərʌɪz/, /mʌlˈtɪmərʌɪz/, U.S. /məlˈtɪməˌraɪz/, /ˈməltəməˌraɪz/
Origin: Formed within English, by derivation. Etymons: multimer n., -ize suffix.
Etymology: < multimer n. + -ize suffix. Compare earlier dimerize v., monomerize v., polymerize v. Compare multimerization n.
Chemistry.
1. intransitive. To become converted into a multimer by the linking together of molecules.
ΘΚΠ
the world > matter > chemistry > atomic chemistry > [verb (intransitive)] > form multimer
multimerize1972
1972 H.-G. Elias in M. B. Huglin Light Scattering from Polymer Solutions ix. 441 Cellulose nitrates multimerize in ethanol at temperatures above 20° C.
1987 Jrnl. Bacteriol. 169 5131 pIM13 is unstable in S. aureus but still multimerizes in that host.
1997 Molecular Endocrinol. 11 1353 Mutations in the IFNγ-activated sequence (GAS), either multimerized or..failed to mediate a PRL response.
2. transitive. To cause to form a multimer.
ΚΠ
1987 Genes & Devel. 1 65 The oligonucleotides were multimerized and linked to a β-globin test gene.
1990 EMBO Jrnl. 9 2538/1 The 21 bp enhancer sequence was multimerized five times and used as a probe.
1996 Jrnl. Virol. 70 2982 The leucine zipper sequence from HIV-1 is capable of multimerizing much larger and otherwise monomeric proteins into extremely stable tetramers.

Derivatives

ˈmultimerized adj.
ΘΚΠ
the world > matter > chemistry > atomic chemistry > [adjective] > relating to molecules > relating to multimer
multimeric1964
multimerized1972
multimerizing1972
1972 H.-G. Elias in M. B. Huglin Light Scattering from Polymer Solutions ix. 398 For the multimerized material, we shall use the following nomenclature.
1995 Jrnl. Cellular Physiol. 164 26 The role of NF-κ-B proteins in regulating transcription from this multimerized oligonucleotide was investigated.
ˈmultimerizing adj.
ΘΚΠ
the world > matter > chemistry > atomic chemistry > [adjective] > relating to molecules > relating to multimer
multimeric1964
multimerized1972
multimerizing1972
1972 H.-G. Elias in M. B. Huglin Light Scattering from Polymer Solutions ix. 400 In light scattering studies of multimerizing solutes, many different concentration dependences of the reciprocal apparent weight average molecular weights may be observed.
1997 Blood 90 3978 Mimicking natural molecules for immune intervention implies the need for multimerizing systems to create multivalent molecules.
This entry has been updated (OED Third Edition, March 2003; most recently modified version published online March 2022).
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v.1972
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